{"doi":"10.1016/j.jad.2020.05.039","title":"Electroconvulsive therapy (ECT) for moderate-severity major depression among the elderly: Data from the pride study","abstract":"BACKGROUND: Electroconvulsive therapy (ECT) is usually reserved for treatment of severe major depressive disorder (MDD), but may be equally effective in the treatment of moderate-severity MDD. This possibility, however, has only been studied to a very limited extent. We therefore investigated the efficacy of ECT after stratifying patients into severe MDD and moderate-severity MDD. METHODS: total scores <12 were considered to have moderate-severity MDD. RESULTS: total score ≤4) (Pearson's 2-sample chi-squared test of difference between groups: p = 0.27). LIMITATIONS: The PRIDE study was not designed to address this research question. CONCLUSIONS: ECT combined with venlafaxine appears to be an effective treatment for moderate-severity MDD. It may be appropriate to expand the indications for ECT to include patients with moderate-severity MDD.","journal":"Journal of Affective Disorders","year":2020,"id":72040,"datarank":0.42498200160843247,"base_score":2.833213344056216,"endowment":2.833213344056216,"self_citation_contribution":0.42498200160843247,"citation_network_contribution":0.0,"self_endowment_contribution":0.42498200160843247,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9377,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":380394,"name":"Maria Speed","orcid":"0000-0002-3356-2080","position":1,"is_corresponding":false},{"id":380395,"name":"Charles H. Kellner","orcid":"0000-0001-9663-3571","position":2,"is_corresponding":false},{"id":324064,"name":"Martina Mueller","orcid":"0000-0003-2041-5142","position":3,"is_corresponding":false},{"id":355630,"name":"Shawn M. McClintock","orcid":"0000-0001-5372-0261","position":4,"is_corresponding":false},{"id":294219,"name":"Mustafa M. Husain","orcid":"0000-0001-9935-1764","position":5,"is_corresponding":false},{"id":381945,"name":"Georgios Petrides","orcid":null,"position":6,"is_corresponding":false},{"id":380396,"name":"W. Vaughn McCall","orcid":"0000-0001-5035-7858","position":7,"is_corresponding":false},{"id":51003,"name":"Sarah H. Lisanby","orcid":"0000-0003-2037-6470","position":8,"is_corresponding":false},{"id":380393,"name":"Søren Dinesen Østergaard","orcid":"0000-0002-8032-6208","position":0,"is_corresponding":true}],"reference_count":40,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-18T21:44:45.622639Z","pmid":"32663942","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}