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A variety of antithrombotic agents, doses, and durations of therapy are being assessed in ongoing randomized controlled trials (RCTs) that focus on outpatients, hospitalized patients in medical wards, and patients critically ill with COVID-19. This paper provides a perspective of the ongoing or completed RCTs related to antithrombotic strategies used in COVID-19, the opportunities and challenges for the clinical trial enterprise, and areas of existing knowledge, as well as data gaps that may motivate the design of future RCTs.","is_dataset_classified":null,"base_score":5.198497031265826,"endowment":5.198497031265826,"datacite_reuse_total":10,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"33741176","pmcid":"PMC7963001","openalex_id":"https://openalex.org/W3138214175","authors":[],"funders":[{"funder_name":"National Institute for Health Research (NIHR)","grant_id":"NIHR201320","title":null},{"funder_name":"National Institute for Health Research (NIHR)","grant_id":"NF-SI-0616-10010","title":null},{"funder_name":"NCATS NIH HHS","grant_id":"UL1 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