{"doi":"10.1016/j.jacadv.2025.101584","title":"Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study","abstract":"BACKGROUND: Social determinants of health (SDOH) may influence 30-day readmission or emergency department (ED) use following acute myocardial infarction (AMI) hospitalizations. Understanding this relationship will promote the development of interventions and policies to reduce readmissions. OBJECTIVES: The aim of the study was to test associations between SDOH and readmission after AMI. METHODS: In this cross-sectional study, we analyzed 753 adults ≥65 years from the Reasons for Geographic and Racial Differences in Stroke study discharged after an AMI between 2003 and 2019. Participants were categorized into 3 groups (0/1, 2, and 3+) based on the number of SDOHs. Poisson models were used to determine relative risks (RRs) and corresponding 95% CI for the associations between SDOH and risk of readmission/ED visit. RESULTS: Of participants, 39.1% (295/753) were women, 27.5% (207/753) were Black, and the median age was 77 years (72-82 years). There were 219 (29.1%) individuals with readmission/ED visit. Of 612 participants with validated SDOH counts, 273 (44.6%) had 0/1 SDOH, 117 (19.1%) had 2 SDOH, and 222 (36.3%) had 3+ SDOH. After adjusting for age and region, increasing number of SDOHs was associated with elevated readmission/ED visit risk (2 SDOH: RR: 1.15; 95% CI: 0.83-1.60; 3+ SDOH: RR: 1.56; 95% CI: 1.20-2.01; P trend = 0.001). Similar results were observed in the fully adjusted model (2 SDOH: RR: 1.12; 95% CI: 0.81-1.56; 3+ SDOH: RR: 1.37; 95% CI: 1.04-1.80; P trend = 0.026). CONCLUSIONS: A cumulative burden of SDOHs is associated with an increased risk of readmission/ED visits after AMI hospitalization. SDOH burden may be a useful approach in identifying individuals presenting with AMI who are most vulnerable for readmission.","journal":"JACC Advances","year":2025,"id":525266,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9008,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":675753,"name":"Orysya Soroka","orcid":"0000-0003-3282-2378","position":1,"is_corresponding":false},{"id":318728,"name":"Laura C. Pinheiro","orcid":"0000-0002-6920-8526","position":2,"is_corresponding":false},{"id":502595,"name":"Madeline R. Sterling","orcid":"0000-0002-9928-4407","position":3,"is_corresponding":false},{"id":370722,"name":"Ernest K. Amankwah","orcid":"0000-0001-7054-9400","position":4,"is_corresponding":false},{"id":494352,"name":"Zaid Almarzooq","orcid":"0000-0001-5413-6219","position":5,"is_corresponding":false},{"id":1268380,"name":"Tracy K. Paul","orcid":"0000-0002-8946-7816","position":6,"is_corresponding":false},{"id":228353,"name":"Parag Goyal","orcid":"0000-0001-7474-3737","position":7,"is_corresponding":false},{"id":228354,"name":"Monika M. Safford","orcid":"0000-0002-3060-0563","position":8,"is_corresponding":false},{"id":1400438,"name":"Koby Amankwah","orcid":null,"position":0,"is_corresponding":true}],"reference_count":36,"raw_metadata":null,"created_at":"2026-07-19T02:50:21.274116Z","pmid":"39951935","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}