{"doi":"10.1016/j.jaad.2020.07.115","title":"Impact of hidradenitis suppurativa on work productivity and associated risk factors","abstract":"To the Editor: Matusiak et al1Matusiak Ł. Bieniek A. Szepietowski J.C. Hidradenitis suppurativa markedly decreases quality of life and professional activity.J Am Acad Dermatol. 2010; 62: 706-708Abstract Full Text Full Text PDF PubMed Scopus (142) Google Scholar showed that hidradenitis suppurativa (HS) caused absenteeism in 58.1% of patients. However, work impairment due to HS is not limited to absenteeism but could also lead to presenteeism (reduced productivity while at work) and at-work productivity loss (absenteeism plus presenteeism). Knowledge of which HS-related factors are associated with absenteeism, presenteeism, and at-work productivity loss is essential. Therefore, we aimed to assess differences between working and nonworking patients with HS; quantify absenteeism, presenteeism, and at-work productivity loss caused by HS; and identify associated risk factors. All newly referred consecutive patients participating in the HiCARE (METc 2018/110), HiSure (METc 2015/074), and HiScreen (MEC-2016-246) registries between April 2015 and July 2019 were included. Patient characteristics, disease severity, patient-reported outcomes, and comorbidities were collected, and the Work Productivity and Activity Impairment questionnaire, specific health problem version, was used to assess the influence of HS on absenteeism, presenteeism, and at-work productivity loss. See the Supplemental Methods (available via Mendeley at https://doi.org/10.17632/6nmk748p89.1) for details on the between-group analyses, multiple imputations, and regression analyses. Overall, 62.0% (523/843) of patients had work at the time of inclusion. The presence of inguinal/gluteal HS, increased HS severity, higher pain scores, the presence of fibromyalgia, and higher depression and anxiety scores were significantly more common in nonworkers (Table I). Twenty-six percent of working patients reported actual work time missed, with a median absenteeism of 0% (95% confidence interval [CI], 0.0-5.3). Workers reported a median presenteeism due to HS of 20% (95% CI, 0.0-50.0) and a median at-work productivity loss of 20.0% (95% CI, 0.0-69.0). Results from the univariate regressions analyses are presented in Supplemental Table I (available via Mendeley at https://doi.org/10.17632/6nmk748p89.1). Pain, Dermatology Life Quality Index, and EuroQol–5 Dimensions scores were significantly associated with presenteeism and at-work productivity loss in the multivariate regression models (Table II).Table IPatient characteristics∗Numbers and percentages may not add up to 100% because of rounding of pooled data.Overall†Percentages in this column are reported as percentages of the overall number of patients. (N = 843)Workers‡Percentages in these columns are presented as percentages of the variable on that row. (n = 523)Nonworkers‡Percentages in these columns are presented as percentages of the variable on that row. (n = 320)P value§P-value calculated between workers and nonworkers.Patient characteristics SexFemale, n (%)604 (71.6)373 (61.8)231 (38.2).79 Age, y, mean (SD)38.0 (12.2)37.3 (11.3)39.0 (13.6).06 Age at onset, y, median (IQR)20.0 (15.0-27.0)20.0 (15.0-27.0)19.0 (15.0-28.0).62Missing, n271512 Disease duration, y, median (IQR)12.5 (6.0-22.0)12.8 (6.5-21.0)12.1 (5.1-25.3).51Missing, n271512 BMI, kg/m2, mean (SD)28.7 (6.3)28.5 (6.1)29.1 (6.5).23 Current or ex-smoker, n (%)643 (76.3)390 (60.7)253 (39.3).16 Positive family history121 (23.8)92 (76.0)29 (24.0)<.001Unknown, n (%)115 (22.6)64 (55.7)51 (44.3)Missing, n335195180 Education level, n (%)Low148 (17.6)65 (43.9)83 (56.1)Medium483 (57.3)300 (62.1)183 (37.9)High212 (25.1)158 (74.5)54 (25.5)<.0001Comorbidities Rheumatoid arthritis, n (%)25 (4.2)12 (48.0)13 (52.0).08Missing, n241134107 Fibromyalgia, n (%)9 (1.5)2 (22.2)7 (77.8).008Missing, n242138104 Spondyloarthritis, n (%)5 (0.9)5 (100.0)0 (0.0)NPMissing, n286139147 Crohn's disease, n (%)35 (5.8)19 (54.3)16 (45.7).18Missing, n240133107 Ulcerative colitis, n (%)5 (0.8)3 (60.0)2 (4","journal":"Journal of the American Academy of Dermatology","year":2020,"id":69230,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":21,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9444,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":366814,"name":"Lisette M. 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Prens","orcid":"0000-0002-8158-660X","position":8,"is_corresponding":false},{"id":366817,"name":"Barbara Horváth","orcid":"0000-0001-8559-3674","position":9,"is_corresponding":false},{"id":249265,"name":"Kelsey R. van Straalen","orcid":"0000-0003-3305-3814","position":0,"is_corresponding":true}],"reference_count":3,"raw_metadata":null,"created_at":"2026-07-18T21:42:22.705573Z","pmid":"32763324","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}