{"doi":"10.1016/j.jaacop.2023.12.004","title":"Impact of SARS-CoV-2 (COVID-19) Infections on Mental Health Diagnoses in Youth With Chronic Illness","abstract":"ObjectiveStressors from the COVID-19 pandemic and limited availability of mental health services have negatively impacted youth mental health in a significant way. In the first year of the pandemic, global prevalence of anxiety and depression increased by roughly 25% in pediatric populations. While the general trend is clear, our research aims to 1) explore the added mental health burden of acute COVID-19 on pediatric patients with chronic conditions and 2) describe the differences in mental health outcomes between pediatric patients with two common chronic conditions (asthma and diabetes) in order to better understand specific factors that may increase susceptibility to mental health concerns.MethodUsing the TriNetX database, we extracted data for all pediatric patients (aged 5-17 years) with a positive SARS-CoV-2 infection (COVID-19) within a one year time frame (April 7, 2021 to April 6, 2022). These patients were divided into four cohorts based on the presence of chronic conditions prior to COVID-19 infection: those with diabetes (n = 1,587), those with asthma (n = 13,217), those with diabetes plus asthma (n = 626), and those without diabetes or asthma (n = 104,427). For all cohorts, we excluded patients with other chronic illness and previous mental health diagnoses using relevant ICD-10 codes. After matching for demographics, comorbid conditions, and BMI, we compared the odds ratios of the following outcomes between cohorts after 6 months: new psychiatric diagnosis, using relevant ICD-10 codes, hospitalization within 1 week, and mortality.ResultsAfter matching, there were statistically significant differences in outcomes between patients with chronic illness and healthy controls after 6 months. Compared to healthy controls, the asthma cohort OR of developing a new psychiatric diagnosis was 1.4 (CI 1.15-1.71, p <0.001) and the diabetes cohort OR was 1.81 (CI 1.11-2.94, p = 0.015). The new psychiatric diagnosis OR of the asthma cohort compared to the diabetes cohort was 0.62 (CI 0.39-0.99, p = 0.045), suggesting that patients in the diabetes cohort were particularly susceptible to additional mental health diagnoses after an acute COVID-19 infection.ConclusionCompared to healthy controls, pediatric asthma patients and pediatric diabetes patients experienced increased odds of developing a new psychiatric diagnosis after an acute COVID-19 infection.","journal":"JAACAP Open","year":2023,"id":387283,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9574,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1033490,"name":"Rina Hung","orcid":"0000-0003-1187-3491","position":1,"is_corresponding":false},{"id":1156062,"name":"Irina Bransteter","orcid":"0009-0009-2982-7515","position":2,"is_corresponding":false},{"id":691109,"name":"Jaime A. Pérez","orcid":"0000-0002-3568-1139","position":3,"is_corresponding":false},{"id":830070,"name":"Tracy Segall","orcid":"0000-0001-5605-7186","position":4,"is_corresponding":false},{"id":718857,"name":"Jessica Surdam","orcid":"0000-0001-8092-8543","position":5,"is_corresponding":false},{"id":1156063,"name":"David W. Miller","orcid":"0009-0007-1049-9860","position":6,"is_corresponding":false},{"id":718858,"name":"Jeffery A. Dusek","orcid":"0000-0001-9581-0564","position":7,"is_corresponding":false},{"id":315573,"name":"Martha Sajatovic","orcid":"0000-0002-3073-668X","position":8,"is_corresponding":false},{"id":944111,"name":"Molly McVoy","orcid":"0000-0003-4967-6055","position":0,"is_corresponding":true}],"reference_count":72,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:18:04.706547Z","pmid":"39552816","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}