{"doi":"10.1016/j.jaacop.2023.11.002","title":"Prospective Follow-Up of Adolescents With and at Risk for Depression: Protocol and Methods of the Identifying Depression Early in Adolescence Risk Stratified Cohort Longitudinal Assessments","abstract":"ObjectiveTo present the protocol and methods for the prospective longitudinal assessments — including clinical and digital phenotyping approaches — of the Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo) study, which comprises Brazilian adolescents stratified at baseline by risk of developing depression or presence of depression.MethodOf 7,720 screened adolescents aged 14-16, we recruited 150 participants (75 boys, 75 girls) based on a composite risk score: 50 with low risk for developing depression (LR), 50 with high risk for developing depression (HR), and 50 with an active untreated major depressive episode (MDD). Three annual follow-up assessments were conducted, involving clinical measures (parent and adolescent-reported questionnaires and psychiatrist assessments), active and passive data sensing via smartphones, and neurobiological measures (neuroimaging and biological material samples). Retention rates were 96% (Wave 1), 94% (Wave 2), and 88% (Wave 3), with no significant differences by sex or group (p > 0.05). Participants highlighted their familiarity with the research team and assessment process as a motivator for sustained engagement.DiscussionThis protocol relied on novel aspects, such as the use of a WhatsApp bot, which is particularly pertinent for low-to-middle-income countries, and the collection of information from diverse sources in a longitudinal design, encompassing clinical data, self-reports, parental reports, GPS data, and ecological momentary assessments. The study engaged adolescents over an extensive period and demonstrated the feasibility of conducting a prospective follow-up study with a risk-enriched cohort of adolescents in a middle-income country, integrating mobile technology with traditional methodologies to enhance longitudinal data collection.","journal":"JAACAP Open","year":2023,"id":348879,"datarank":0.44071774017696397,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.06798174270876386,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.06798174270876386,"corpus_percentile":57.46886361878239,"corpus_rank":5499,"citation_count":11,"citer_count":2,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.7219,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1091617,"name":"Anna Viduani","orcid":"0000-0002-6289-6397","position":1,"is_corresponding":false},{"id":1091618,"name":"Claudia Buchweitz","orcid":"0000-0002-6213-9724","position":2,"is_corresponding":false},{"id":1092117,"name":"Rivka Pereira","orcid":null,"position":3,"is_corresponding":false},{"id":1092118,"name":"Aline Zimerman","orcid":null,"position":4,"is_corresponding":false},{"id":1091619,"name":"Guilherme Rodriguez Amando","orcid":"0000-0002-3260-8948","position":5,"is_corresponding":false},{"id":1091620,"name":"Victor Cosenza","orcid":"0000-0001-6981-0835","position":6,"is_corresponding":false},{"id":1091621,"name":"Leonardo Z. 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Reckziegel","orcid":"0000-0002-7347-0527","position":11,"is_corresponding":false},{"id":1092120,"name":"Fernanda Rohrsetzer","orcid":null,"position":12,"is_corresponding":false},{"id":1091625,"name":"Laila Souza","orcid":"0009-0002-7203-6064","position":13,"is_corresponding":false},{"id":1091626,"name":"André Comiran Tonon","orcid":"0000-0003-4818-3144","position":14,"is_corresponding":false},{"id":1092121,"name":"Marina Tuerlinckx Costa-Valle","orcid":null,"position":15,"is_corresponding":false},{"id":1091627,"name":"Zuzanna Zajkowska","orcid":"0000-0002-5214-305X","position":16,"is_corresponding":false},{"id":1091628,"name":"Ricardo Araújo","orcid":"0000-0003-0514-8883","position":17,"is_corresponding":false},{"id":257904,"name":"Tobias U. 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