{"doi":"10.1016/j.inpsyc.2026.100223","title":"Research waste among randomized controlled trials of delirium: A cross-sectional study","abstract":null,"journal":"International Psychogeriatrics","year":2026,"id":612771,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1370559,"name":"Shiqi Wang","orcid":"0000-0002-3583-959X","position":1,"is_corresponding":false},{"id":869066,"name":"Weiyi Li","orcid":"0000-0002-9988-797X","position":2,"is_corresponding":false},{"id":751280,"name":"Jianxiong Wang","orcid":"0000-0002-6861-7483","position":3,"is_corresponding":false},{"id":1577902,"name":"Yaqian Gao","orcid":null,"position":4,"is_corresponding":false},{"id":409245,"name":"Yue Hu","orcid":"0000-0002-9240-6483","position":5,"is_corresponding":false},{"id":1577901,"name":"Xinxing Fei","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Research waste among randomized controlled trials of delirium: A cross-sectional study","abstract":"OBJECTIVES: To assess the prevalence, characteristics, and associated factors of research waste among randomized controlled trials (RCTs) of delirium. DESIGN: Cross-sectional study. SETTING: Data derived from ClinicalTrials.gov. PARTICIPANTS: 126 phase III/IV delirium RCTs registered between 2000 and 2024. MEASUREMENTS: Publication status was determined via PubMed and Google Scholar. Reporting adequacy was evaluated using the CONSORT reporting guideline checklist, and methodological flaws were assessed using the Cochrane Risk of Bias tool. Research waste was defined as meeting any of the following criteria: non-publication, inadequate reporting (CONSORT compliance <75%), or avoidable design flaws (high/unclear risk per Cochrane criteria). RESULTS: Research waste was highly prevalent, affecting 92.9% of RCTs. Only 22.2% of trials were fully published. Among published trials, reporting rates for key methodological details (allocation concealment, blinding) were below 80%, and 67.9% had avoidable design flaws. A large sample size (≥100 participants) was independently associated with a higher likelihood of publication (adjusted OR=4.23, 95% CI: 1.43-14.41, P = 0.013), whereas industry or other external funding was associated with a lower likelihood (adjusted OR=0.05, 95% CI: 0.00-0.53, P = 0.027). International and multicenter designs showed a trend toward reducing research waste but were not statistically significant in the multivariate model. CONCLUSIONS: Phase III/IV delirium RCTs exhibit severe research waste, highlighting a critical gap in evidence generation for this geriatric syndrome. Mandating disclosure of results, enhancing reporting transparency, and prioritizing high-quality, large-scale collaborative research are urgently needed to optimize resource allocation and improve outcomes for this vulnerable population.","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"42209336","pmcid":null,"openalex_id":"https://openalex.org/W7162692489","authors":[],"funders":[{"funder_name":"Southwest Medical University","grant_id":"2025012","title":null},{"funder_name":"Southwest Medical University","grant_id":"2025008","title":null},{"funder_name":"Sichuan Provincial Science and Technology Support Program","grant_id":"2026NSFSC1568","title":null}],"total_grants":3,"fwci":9.9287,"citation_percentile":0.97900817,"influential_citations":0,"citation_trend":[{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"https://www.intpsychogeriatrics.org/article/S1041-6102(26)00041-4/pdf","host_type":"journal"},{"url":"https://www.intpsychogeriatrics.org/article/S1041-6102(26)00041-4/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1041610226000414?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1041610226000414?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.inpsyc.2026.100223","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/42209336","host_type":"repository"}],"fields_of_study":["Intensive Care Unit Cognitive Disorders","Alcoholism and Thiamine Deficiency","Climate Change and Health Impacts"],"mesh_terms":[],"keywords":["Randomized controlled trial","Research design","MEDLINE","Clinical trial","Research methodology","Delirium","Publication Bias","Research Waste","Reporting Quality"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T04:54:14.265976Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}