{"doi":"10.1016/j.ijid.2023.01.034","title":"Consequences of Shigella infection in young children: a systematic review","abstract":null,"journal":"International Journal of Infectious Diseases","year":2023,"id":621294,"datarank":0.5742962094733643,"base_score":3.828641396489095,"endowment":3.828641396489095,"self_citation_contribution":0.5742962094733643,"citation_network_contribution":0.0,"self_endowment_contribution":0.5742962094733643,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":45,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1090772,"name":"Miranda L. M. Delawalla","orcid":"0000-0002-6906-2707","position":1,"is_corresponding":false},{"id":1604181,"name":"Fatima Al-Shimari","orcid":null,"position":2,"is_corresponding":false},{"id":281669,"name":"Calman A. MacLennan","orcid":"0000-0001-9694-0846","position":3,"is_corresponding":false},{"id":1604182,"name":"Kirsten S. Vannice","orcid":null,"position":4,"is_corresponding":false},{"id":515245,"name":"Patricia B. Pavlinac","orcid":"0000-0002-0051-9131","position":5,"is_corresponding":false},{"id":607005,"name":"Tanya Libby","orcid":"0000-0002-8569-9206","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Consequences of Shigella infection in young children: a systematic review","abstract":"OBJECTIVES: We conducted a systematic review of the longitudinal consequences of Shigella infection in children to inform the value proposition for an effective vaccine. METHODS: We searched PubMed and Embase for studies published from January 01, 1980 to December 12, 2022 and conducted in low- and middle-income countries that included longitudinal follow-up after Shigella detection among children aged <5 years, irrespective of language. We collected data on all outcomes subsequent to Shigella detection, except mortality. RESULTS: Of 2627 papers identified, 52 met inclusion criteria. The median sample size of children aged <5 years was 66 (range 5-2172). Data were collected in 20 countries; 56% (n = 29) of the publications included Bangladesh. The most common outcomes related to diarrhea (n = 20), linear growth (n = 14), and the mean total cost of a Shigella episode (n = 4; range: $ 6.22-31.10). Among children with Shigella diarrhea, 2.9-61.1% developed persistent diarrhea (≥14 days); the persistence was significantly more likely among children who were malnourished, had bloody stool, or had multidrug-resistant Shigella. Cumulative Shigella infections over the first 2 years of life contributed to the greatest loss in length-for-age z-score. CONCLUSION: We identified evidence that Shigella is associated with persistent diarrhea, linear growth faltering, and economic impact to the family.","is_dataset_classified":null,"base_score":3.828641396489095,"endowment":3.828641396489095,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36736579","pmcid":"PMC10017352","openalex_id":"https://openalex.org/W4318612361","authors":[],"funders":[{"funder_name":"NIAAA NIH HHS","grant_id":"T32 AA007455","title":null},{"funder_name":"NIEHS NIH HHS","grant_id":"T32 ES015459","title":null},{"funder_name":"National Institutes of Health","grant_id":"5T32ES015459-09","title":"Biostatistics, Epidemiologic & Bioinformatic Training in Environmental Health"}],"total_grants":3,"fwci":4.2171,"citation_percentile":0.96296296,"influential_citations":0,"citation_trend":[{"year":2023,"count":4},{"year":2024,"count":17},{"year":2025,"count":18},{"year":2026,"count":6}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"http://www.ijidonline.com/article/S1201971223000346/pdf","host_type":"journal"},{"url":"http://www.ijidonline.com/article/S1201971223000346/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1201971223000346?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1201971223000346?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.ijid.2023.01.034","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36736579","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10017352","host_type":"repository"},{"url":"https://doaj.org/article/7bd16ee3e933434fb5a469f0616405fe","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10017352/pdf/main.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC10017352","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC10017352?pdf=render","host_type":"Europe_PMC"},{"url":"http://dx.doi.org/10.1016/j.ijid.2023.01.034","host_type":""}],"fields_of_study":["Escherichia coli research studies","Viral gastroenteritis research and epidemiology","Child Nutrition and Water Access","03 medical and health sciences","0302 clinical medicine","Humans","Child","Infant","Child, Preschool","Dysentery, Bacillary","Diarrhea","Shigella","Bangladesh","Malnutrition"],"mesh_terms":["Bangladesh","Child","Child, Preschool","Diarrhea","Dysentery, Bacillary","Humans","Infant","Shigella","Malnutrition"],"keywords":["Shigella","Medicine","Biology","Salmonella","Genetics","Bacteria","Vaccine","Diarrhea","Stunting","Enteric","Growth Faltering","Bangladesh","Malnutrition","Infant","Infectious and parasitic diseases","RC109-216","Review","Child, Preschool","Humans","Child","Dysentery, Bacillary"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"No poverty"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-03T13:58:07.566248Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}