{"doi":"10.1016/j.ijid.2020.10.088","title":"Association of schistosomiasis and HIV infections: A systematic review and meta-analysis","abstract":"BACKGROUND: Female genital schistosomiasis (FGS) affects up to 56 million women in sub-Saharan Africa and may increase risk of HIV infection. METHODS: To assess the association of schistosomiasis with HIV infection, peer-reviewed literature published until 31 December 2018 was examined and a pooled estimate for the odds ratio was generated using Bayesian random effects models. RESULTS: Of the 364 abstracts that were identified, 26 were included in the summary. Eight reported odds ratios of the association between schistosomiasis and HIV; one reported a transmission hazard ratio of 1.8 (95% CI, 1.2-2.6) among women and 1.4 (95% CI, 1.0-1.9) among men; 11 described the prevalence of schistosomiasis among HIV-positive people (range, 1.5-36.6%); and six reported the prevalence of HIV among people with schistosomiasis (range, 5.8-57.3%). Six studies were selected for quantitative analysis. The pooled estimate for the odds ratio of HIV among people with schistosomiasis was 2.3 (95% CI, 1.2-4.3). CONCLUSIONS: A significant association of schistosomiasis with HIV was found. However, a specific summary estimate for FGS could not be generated. A research agenda was provided to determine the effect of FGS on HIV infection. The WHO's policy on mass drug administration for schistosomiasis may prevent HIV.","journal":"International Journal of Infectious Diseases","year":2020,"id":55852,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":90,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6246,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":232715,"name":"Charles E. Rose","orcid":"0000-0003-2359-8060","position":1,"is_corresponding":false},{"id":289422,"name":"Eyrun Floerecke Kjetland","orcid":"0000-0002-5552-1095","position":2,"is_corresponding":false},{"id":268460,"name":"Jennifer A. Downs","orcid":"0000-0001-9537-204X","position":3,"is_corresponding":false},{"id":290496,"name":"Pamela Sabina Mbabazi","orcid":null,"position":4,"is_corresponding":false},{"id":289423,"name":"Keith Sabin","orcid":"0000-0002-2290-8621","position":5,"is_corresponding":false},{"id":289424,"name":"Wairimu Chege","orcid":"0000-0003-3859-0977","position":6,"is_corresponding":false},{"id":290497,"name":"D. Heather Watts","orcid":null,"position":7,"is_corresponding":false},{"id":289425,"name":"W. Evan Secor","orcid":"0000-0003-0584-5961","position":8,"is_corresponding":false},{"id":226689,"name":"Pragna Patel","orcid":"0000-0003-1386-8194","position":0,"is_corresponding":true}],"reference_count":76,"raw_metadata":null,"created_at":"2026-07-18T21:05:29.672878Z","pmid":"33157296","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}