{"doi":"10.1016/j.hroo.2024.02.001","title":"Trends in the 30-year span of noninfectious cardiovascular implantable electronic device complications in Olmsted County","abstract":"BackgroundCardiovascular implantable electronic devices (CIEDs) such as permanent pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy devices alleviate morbidity and mortality in various diseases. There is a paucity of real-world data on CIED complications and trendsObjectivesDescribe trends in noninfectious CIED complications over the past three decades in Olmsted CountyMethodsThe Rochester Epidemiology Project is a medical records linkage system comprising records of over 500,000 residents of Olmsted County from 1966-current. CIED implants between 1988-2018 were determined. Trends in noninfectious complications within 30 days of implant were analyzedResults157 out of 2536 (6.2%) patients who received CIED experienced device complications. 2.7% of the implants had major complications requiring intervention. Lead dislodgement was the most common (2.8%), followed by hematoma (1.7%). Complications went up from 1988 to 2005, then showed a downtrend until 2018, driven by a decline in hematomas in the last decade (p<0.01). Those with complications were more likely to have prosthetic valves. Obesity appeared to have a protective effect in a multivariate regression model. The mean Charlson comorbidity score has trended up over the 30 yearsConclusionsOur study describes a real-world trend of CIED complications over three decades. Lead dislodgements and hematomas were the most common complications. Complications have declined over the last decade due to safer practices and a better understanding of anticoagulant management Cardiovascular implantable electronic devices (CIEDs) such as permanent pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy devices alleviate morbidity and mortality in various diseases. There is a paucity of real-world data on CIED complications and trends Describe trends in noninfectious CIED complications over the past three decades in Olmsted County The Rochester Epidemiology Project is a medical records linkage system comprising records of over 500,000 residents of Olmsted County from 1966-current. CIED implants between 1988-2018 were determined. Trends in noninfectious complications within 30 days of implant were analyzed 157 out of 2536 (6.2%) patients who received CIED experienced device complications. 2.7% of the implants had major complications requiring intervention. Lead dislodgement was the most common (2.8%), followed by hematoma (1.7%). Complications went up from 1988 to 2005, then showed a downtrend until 2018, driven by a decline in hematomas in the last decade (p<0.01). Those with complications were more likely to have prosthetic valves. Obesity appeared to have a protective effect in a multivariate regression model. The mean Charlson comorbidity score has trended up over the 30 years Our study describes a real-world trend of CIED complications over three decades. Lead dislodgements and hematomas were the most common complications. Complications have declined over the last decade due to safer practices and a better understanding of anticoagulant management","journal":"Heart Rhythm O2","year":2024,"id":473039,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.943,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":698844,"name":"Vaibhav R. Vaidya","orcid":null,"position":1,"is_corresponding":false},{"id":698337,"name":"Mingyan Dai","orcid":"0000-0001-9145-8663","position":2,"is_corresponding":false},{"id":1308873,"name":"Pragyat Futela","orcid":"0000-0001-6739-0718","position":3,"is_corresponding":false},{"id":1292547,"name":"Rahul Mishra","orcid":"0009-0002-3575-9140","position":4,"is_corresponding":false},{"id":287453,"name":"David O. Hodge","orcid":null,"position":5,"is_corresponding":false},{"id":698338,"name":"Abhishek Deshmukh","orcid":"0000-0002-9560-1102","position":6,"is_corresponding":false},{"id":237802,"name":"Siva K. Mulpuru","orcid":"0000-0002-7694-3617","position":7,"is_corresponding":false},{"id":268244,"name":"Paul A. Friedman","orcid":"0000-0001-5052-2948","position":8,"is_corresponding":false},{"id":237798,"name":"Yong‐Mei Cha","orcid":"0000-0002-5897-9464","position":9,"is_corresponding":false},{"id":368927,"name":"Gurukripa N. Kowlgi","orcid":"0000-0002-0913-3497","position":0,"is_corresponding":true}],"reference_count":42,"raw_metadata":null,"created_at":"2026-07-19T02:06:01.000126Z","pmid":"38560372","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}