{"doi":"10.1016/j.hroo.2022.08.010","title":"American Indians and atrial fibrillation","abstract":"The American Indian population is known to experience high rates of cardiovascular disease and have a heightened vulnerability to severe outcomes driven by an overall poor health status and lower access to quality health care. Our group has previously published an analysis demonstrating that American Indians have the highest risk of atrial fibrillation (AF), as well as of AF-related stroke, when compared with other races and ethnicities. Despite this, AF in this population has not been extensively studied and additional publications are scarce. Our review article provides an up-to-date summary of the relevant literature addressing the relationship between race, ethnicity, and AF by focusing on American Indians. The American Indian population is known to experience high rates of cardiovascular disease and have a heightened vulnerability to severe outcomes driven by an overall poor health status and lower access to quality health care. Our group has previously published an analysis demonstrating that American Indians have the highest risk of atrial fibrillation (AF), as well as of AF-related stroke, when compared with other races and ethnicities. Despite this, AF in this population has not been extensively studied and additional publications are scarce. Our review article provides an up-to-date summary of the relevant literature addressing the relationship between race, ethnicity, and AF by focusing on American Indians. Key Findings▪American Indians and Alaska Natives experience high rates of cardiovascular disease.▪They also have the highest risk of atrial fibrillation (AF) and AF-related stroke compared with other racial and ethnic groups.▪We provide an up-to-date summary on the relationship between race, ethnicity, and AF with a focus on American Indians and Alaska Natives. ▪American Indians and Alaska Natives experience high rates of cardiovascular disease.▪They also have the highest risk of atrial fibrillation (AF) and AF-related stroke compared with other racial and ethnic groups.▪We provide an up-to-date summary on the relationship between race, ethnicity, and AF with a focus on American Indians and Alaska Natives. It is important to discuss the risks and consequences of atrial fibrillation (AF) in American Indian and Alaska Native populations by first considering the broader context of overall cardiovascular health. In general, American Indians experience particularly high rates of cardiovascular disease (CVD).1Breathett K. Sims M. Gross M. et al.Cardiovascular health in American Indians and Alaska Natives: a scientific statement from the American Heart Association.Circulation. 2020; 141: E948-E959Crossref PubMed Scopus (47) Google Scholar,2Howard B.V. Lee E.T. Cowan L.D. et al.Rising tide of cardiovascular disease in American Indians: the Strong Heart Study.Circulation. 1999; 99: 2389-2395Crossref PubMed Scopus (361) Google Scholar American Indians develop CVD at earlier ages than whites, and CVD is the primary cause of death in over one-third of American Indian deaths occurring before the age of 65 years.1Breathett K. Sims M. Gross M. et al.Cardiovascular health in American Indians and Alaska Natives: a scientific statement from the American Heart Association.Circulation. 2020; 141: E948-E959Crossref PubMed Scopus (47) Google Scholar This has translated into a lower life expectancy that is 5.5 years less in American Indians than non–American Indians.3Indian Health Service. Disparities.https://www.ihs.gov/newsroom/factsheets/disparities/Date accessed: May 10, 2022Google Scholar A variety of risk factors have been shown to contribute to this heightened rate of CVD. American Indians have the highest rates of diabetes mellitus, hypertension, chronic kidney disease, smoking, and coronary heart disease in the United States.1Breathett K. Sims M. Gross M. et al.Cardiovascular health in American Indians and Alaska Natives: a scientific statement from the American Heart Association.Circulation. 2020; 141: E948-E959Crossref PubMe","journal":"Heart Rhythm O2","year":2022,"id":276143,"datarank":0.3453877639491069,"base_score":2.302585092994046,"endowment":2.302585092994046,"self_citation_contribution":0.3453877639491069,"citation_network_contribution":0.0,"self_endowment_contribution":0.3453877639491069,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9648,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":266842,"name":"Gregory M. Marcus","orcid":"0000-0001-5197-7696","position":1,"is_corresponding":false},{"id":946246,"name":"José M. Sánchez","orcid":"0000-0003-1331-2460","position":0,"is_corresponding":true}],"reference_count":70,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T00:28:26.545826Z","pmid":"36588996","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}