{"doi":"10.1016/j.gimo.2024.101874","title":"Addressing the need for genetic cancer risk assessment in Mexico: From establishment of a formal program to delivery innovation and expansion","abstract":"Purpose: The purpose of this manuscript is to show the process of the establishment and adaptation of an oncogenetics program in Mexico. Methods: The oncogentics program at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán was established as a traditional in-person service and adapted to include telemedicine counseling to expand services to other hospitals and persists as a mixed counseling model with research/commercial genetic testing. Results: A total of 2222 participants were included with a median age of 47 years and 77.6% were women; 64% and 36% were enrolled in person and by phone, respectively; 91.1% had research testing, 4.7% commercial testing, 2% complementary pharma testing, and 2.1% had more than 1 testing. Results disclosure was by phone for 49.6%, in person for 43.3%, and by videocall for 7.1% of the cases. Cascade testing proportion was similar in both groups (88%), and 14.8% probands and 40.8% family members had a positive result for a pathogenic cancer susceptibility gene variant. Conclusion: Our results demonstrated that genetic cancer risk assessment is feasible in limited resources settings and provide evidence that telemedicine is effective and can be used as an alternative in real-world populations. Our model could be adapted and potentially replicated in other institutions and countries that face similar barriers for health care.","journal":"Genetics in Medicine Open","year":2024,"id":468637,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9552,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1118378,"name":"José Luis Rodríguez-Olivares","orcid":"0000-0002-5272-1331","position":1,"is_corresponding":false},{"id":1302144,"name":"Alfredo Ramírez-González","orcid":null,"position":2,"is_corresponding":false},{"id":1302145,"name":"José Manuel Moreno-Mirón","orcid":null,"position":3,"is_corresponding":false},{"id":1302146,"name":"Alex Lagunas-Medina","orcid":null,"position":4,"is_corresponding":false},{"id":1301694,"name":"José Carlos Peñafort-Zamora","orcid":"0009-0002-1573-232X","position":5,"is_corresponding":false},{"id":470864,"name":"Jazmín Arteaga‐Vázquez","orcid":"0000-0003-3090-0299","position":6,"is_corresponding":false},{"id":1187055,"name":"Gregorio Quintero Beuló","orcid":"0000-0003-0920-6200","position":7,"is_corresponding":false},{"id":1301695,"name":"Roberto Sánchez-Reyes","orcid":"0000-0003-1121-0604","position":8,"is_corresponding":false},{"id":107682,"name":"Jeffrey N. Weitzel","orcid":"0000-0001-6714-092X","position":9,"is_corresponding":false},{"id":383479,"name":"Yanin Chávarri-Guerra","orcid":"0000-0003-0792-1817","position":0,"is_corresponding":true}],"reference_count":18,"raw_metadata":null,"created_at":"2026-07-19T02:05:23.500722Z","pmid":"39712971","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}