{"doi":"10.1016/j.gimo.2024.100945","title":"P063: A second-generation polygenic risk score (PRS) based on genetic ancestry improves breast cancer (BC) risk prediction for all ancestries*","abstract":null,"journal":"Genetics in Medicine Open","year":2024,"id":594713,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":564672,"name":"Elisha Hughes","orcid":"0000-0002-3145-3913","position":1,"is_corresponding":false},{"id":112062,"name":"Dmitry Pruss","orcid":null,"position":2,"is_corresponding":false},{"id":1522551,"name":"Matthew Kucera","orcid":null,"position":3,"is_corresponding":false},{"id":1522552,"name":"Benjamin Roa","orcid":null,"position":4,"is_corresponding":false},{"id":1522553,"name":"Thaddeus Judkins","orcid":null,"position":5,"is_corresponding":false},{"id":1226671,"name":"Thomas Slavin","orcid":null,"position":6,"is_corresponding":false},{"id":1522554,"name":"Victor Abkevich","orcid":null,"position":7,"is_corresponding":false},{"id":1522555,"name":"Ryan Hoff","orcid":null,"position":8,"is_corresponding":false},{"id":1522556,"name":"Srikanth Jammulapati","orcid":null,"position":9,"is_corresponding":false},{"id":498959,"name":"Susanne Wagner","orcid":"0000-0002-1559-7538","position":10,"is_corresponding":false},{"id":1522557,"name":"Dale Muzzey","orcid":null,"position":11,"is_corresponding":false},{"id":1522558,"name":"Jerry Lanchbury","orcid":null,"position":12,"is_corresponding":false},{"id":374316,"name":"Alexander Gutin","orcid":"0000-0002-6565-3729","position":13,"is_corresponding":false},{"id":660486,"name":"Timothy Simmons","orcid":"0000-0001-5741-4763","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"P063: A second-generation polygenic risk score (PRS) based on genetic ancestry improves breast cancer (BC) risk prediction for all ancestries*","abstract":"Common genetic variants, mainly single nucleotide polymorphisms (SNPs), explain substantial genetic susceptibility to BC. PRS have been developed to quantify the combined effects of BC-associated SNPs, providing important information about BC risk. 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