{"doi":"10.1016/j.gendis.2023.06.032","title":"Molecular mechanisms of cisplatin resistance in ovarian cancer","abstract":null,"journal":"Genes & Diseases","year":2024,"id":607278,"datarank":0.5050943744979712,"base_score":3.367295829986474,"endowment":3.367295829986474,"self_citation_contribution":0.5050943744979712,"citation_network_contribution":0.0,"self_endowment_contribution":0.5050943744979712,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":28,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1559265,"name":"Chenjun Shen","orcid":null,"position":1,"is_corresponding":false},{"id":1559267,"name":"Maowei Ni","orcid":null,"position":2,"is_corresponding":false},{"id":535074,"name":"Lili Huang","orcid":"0000-0001-7437-5997","position":3,"is_corresponding":false},{"id":1559271,"name":"Hongtao Hu","orcid":null,"position":4,"is_corresponding":false},{"id":1559273,"name":"Qinhui Dai","orcid":null,"position":5,"is_corresponding":false},{"id":1559274,"name":"Huajun Zhao","orcid":null,"position":6,"is_corresponding":false},{"id":1437939,"name":"Zhihui Zhu","orcid":"0000-0002-0037-194X","position":7,"is_corresponding":false},{"id":1559264,"name":"Chenying Jiang","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Molecular mechanisms of cisplatin resistance in ovarian cancer","abstract":"Ovarian cancer is one of the most common malignant tumors of the female reproductive system. The majority of patients with advanced ovarian cancer are mainly treated with cisplatin-based chemotherapy. As the most widely used first-line anti-neoplastic drug, cisplatin produces therapeutic effects through multiple mechanisms. However, during clinical treatment, cisplatin resistance has gradually emerged, representing a challenge for patient outcome improvement. The mechanism of cisplatin resistance, while known to be complex and involve many processes, remains unclear. We hope to provide a new direction for pre-clinical and clinical studies through this review on the mechanism of ovarian cancer cisplatin resistance and methods to overcome drug resistance.","is_dataset_classified":null,"base_score":3.2188758248682006,"endowment":3.2188758248682006,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39224110","pmcid":"PMC11367050","openalex_id":"https://openalex.org/W4385496679","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"","title":null}],"total_grants":1,"fwci":4.9317,"citation_percentile":0.95881946,"influential_citations":0,"citation_trend":[{"year":2024,"count":3},{"year":2025,"count":9},{"year":2026,"count":12}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1016/j.gendis.2023.06.032","host_type":"journal"},{"url":"https://doi.org/10.1016/j.gendis.2023.06.032","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2352304223003446?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2352304223003446?httpAccept=text/plain","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39224110","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11367050","host_type":"repository"},{"url":"https://doaj.org/article/8a78d6a5bca2487ab97c9f7ddeb5100c","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11367050/pdf/main.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC11367050","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC11367050?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Ovarian cancer diagnosis and treatment","PARP inhibition in cancer therapy","Genomics, phytochemicals, and oxidative stress"],"mesh_terms":[],"keywords":["Cisplatin","Ovarian cancer","Mechanism (biology)","Drug resistance","Oncology","Medicine","Chemotherapy","Internal medicine","Cancer","Bioinformatics","Cancer research","Pharmacology","Biology","Genetics","Molecular mechanisms","Therapeutic strategies"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T06:05:27.574953Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}