{"doi":"10.1016/j.focus.2024.100302","title":"E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis","abstract":"Introduction Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. Although the U.S. Food and Drug Administration–approved products and evidence-based methods exist for smoking cessation, people who smoke might use E-cigarettes as cessation aids. Whether E-cigarette use is associated with the use of evidence-based methods is unknown, particularly among American Indian/Alaska Native individuals. Methods Using survey data collected in 2016 from 289 adult American Indian people who smoke and who reported a previous cessation attempt, the authors conducted multivariate logistic regression analyses to assess the associations between E-cigarette use and evidence-based cessation methods. Analyses were performed in 2023. Results Individuals who currently or formerly used E-cigarettes were significantly more likely to report using nicotine replacement therapy during their last quit attempt than those who did not use E-cigarettes (current versus never AOR=4.6, 95% CI=1.9, 11.9; past versus never AOR=4.6, 95% CI=2.2, 9.8; p <0.001). Current and former E-cigarette use was significantly associated with prescription use in the unadjusted analysis but lost significance in the adjusted analysis (current versus never AOR=3.1, 95% CI=1.0, 10.5; past versus never AOR=2.7, 95% CI=1.1, 7.9; p >0.05). Individuals with current or former use of E-cigarettes were significantly less likely than individuals who never used E-cigarettes to use the cold turkey method (unassisted cessation) (current versus never AOR=0.3, 95% CI=0.2, 0.6; past versus never AOR=0.3, 95% CI=0.1, 0.7; p <0.01). Conclusions These results suggest that persons who use E-cigarettes are more likely than individuals who do not use E-cigarettes to previously have tried nicotine replacement therapy but less likely to use the cold turkey method. A larger study is needed to determine whether individuals who use E-cigarettes are also more likely to have tried prescription medication for smoking cessation. Whether E-cigarette use impedes or encourages the use of evidence-based cessation methods is unknown.","journal":"AJPM Focus","year":2024,"id":506693,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9508,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":782360,"name":"Dorothy A. Rhoades","orcid":"0000-0002-4031-3576","position":1,"is_corresponding":false},{"id":925528,"name":"Justin Dvorak","orcid":"0000-0001-5018-7940","position":2,"is_corresponding":false},{"id":416400,"name":"Kai Ding","orcid":"0000-0001-9475-437X","position":3,"is_corresponding":false},{"id":1358181,"name":"Noah Collins","orcid":null,"position":4,"is_corresponding":false},{"id":1141510,"name":"Alexandra Blair","orcid":"0000-0002-8555-0399","position":5,"is_corresponding":false},{"id":727040,"name":"Mark P. Doescher","orcid":"0000-0003-1631-0428","position":6,"is_corresponding":false},{"id":530392,"name":"Ashley L. Comiford","orcid":"0000-0001-6951-4737","position":0,"is_corresponding":true}],"reference_count":45,"raw_metadata":null,"created_at":"2026-07-19T02:10:54.646711Z","pmid":"40458594","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}