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GA could not inhibit the growth of S. aureus, but the secretion of Hla by S. aureus was significantly inhibited by low concentrations of GA in a dose-dependent manner. Furthermore, in vivo data show that GA provides protection against staphylococcal pneumonia in a murine model system.","is_dataset_classified":null,"base_score":3.7376696182833684,"endowment":3.7376696182833684,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"22085765","pmcid":null,"openalex_id":"https://openalex.org/W2050750095","authors":[],"funders":[],"total_grants":0,"fwci":4.0914,"citation_percentile":0.92727172,"influential_citations":0,"citation_trend":[{"year":2012,"count":4},{"year":2013,"count":5},{"year":2015,"count":1},{"year":2016,"count":5},{"year":2017,"count":2},{"year":2018,"count":2},{"year":2019,"count":2},{"year":2020,"count":5},{"year":2021,"count":3},{"year":2022,"count":4},{"year":2023,"count":3},{"year":2024,"count":4},{"year":2025,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0367326X11002759?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0367326X11002759?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.fitote.2011.10.018","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/22085765","host_type":"repository"}],"fields_of_study":["Pharmacological Effects of Natural Compounds","Ginseng Biological Effects and Applications","Phytochemistry and biological activity of medicinal plants","Animals","Anti-Bacterial Agents","Cell Line, Tumor","Glycyrrhetinic Acid","Humans","Male","Mice","Mice, Inbred C57BL","Microbial Sensitivity Tests","Molecular Structure","Pneumonia, Bacterial","Real-Time Polymerase Chain Reaction","Reverse Transcriptase Polymerase Chain Reaction","Staphylococcal Infections","Staphylococcus aureus"],"mesh_terms":["Animals","Anti-Bacterial Agents","Glycyrrhetinic Acid","Humans","Male","Mice, Inbred C57BL","Microbial Sensitivity Tests","Staphylococcal Infections","Staphylococcus aureus","Molecular Structure","Pneumonia, Bacterial","Reverse Transcriptase Polymerase Chain Reaction","Cell Line, Tumor","Mice","Real-Time Polymerase Chain Reaction"],"keywords":["Staphylococcus aureus","In vivo","Microbiology","Antimicrobial","Pneumonia","Hemolysin","Staphylococcal infections","Biology","Chemistry","Virulence","Medicine","Bacteria","Biochemistry","Gene"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-25T16:30:55.672036Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}