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As functional parameters of the receptor, such as coupling to potassium channels, are not affected by the interaction with PSD‐95, the association may serve to localize the receptor to postsynaptic sites.</jats:p>","journal":"FEBS Letters","year":2007,"id":642670,"datarank":0.9689931710204757,"base_score":2.9444389791664403,"endowment":2.9444389791664403,"self_citation_contribution":0.44166584687496613,"citation_network_contribution":0.5273273241455095,"self_endowment_contribution":0.44166584687496613,"citer_contribution":0.5273273241455095,"corpus_percentile":null,"corpus_rank":null,"citation_count":18,"citer_count":13,"citers_with_citation_signal":13,"citers_with_endowment":13,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1671797,"name":"Stefan Kindler","orcid":null,"position":1,"is_corresponding":false},{"id":18984,"name":"Stefan Schulz","orcid":"0000-0002-4810-324X","position":2,"is_corresponding":false},{"id":219911,"name":"Friedrich Buck","orcid":null,"position":3,"is_corresponding":false},{"id":120515,"name":"Dietmar Richter","orcid":null,"position":4,"is_corresponding":false},{"id":120511,"name":"Hans-Jürgen Kreienkamp","orcid":null,"position":5,"is_corresponding":false},{"id":1671796,"name":"Marcus Christenn","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Interaction of brain somatostatin receptors with the PDZ domains of PSD‐95","abstract":"<jats:p>Using peptide affinity purification, we identified an interaction between somatostatin receptors SSTR4 and SSTR1 and PDZ domains 1 and 2 of the postsynaptic proteins postsynaptic density protein of 95 kDa (PSD‐95) and PSD‐93. The existence of the SSTR4/PSD‐95 complex was verified by coimmunoprecipitation from transfected cells and solubilized brain membranes. In neurons, dendritically localized SSTR4 partially colocalizes with postsynaptic PSD‐95. As functional parameters of the receptor, such as coupling to potassium channels, are not affected by the interaction with PSD‐95, the association may serve to localize the receptor to postsynaptic sites.</jats:p>","is_dataset_classified":null,"base_score":2.9444389791664403,"endowment":2.9444389791664403,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17950729","pmcid":null,"openalex_id":"https://openalex.org/W2091495159","authors":[],"funders":[],"total_grants":0,"fwci":0.7543,"citation_percentile":0.69591862,"influential_citations":0,"citation_trend":[{"year":2013,"count":2},{"year":2014,"count":1},{"year":2015,"count":1},{"year":2017,"count":1},{"year":2018,"count":1},{"year":2020,"count":1},{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":1}],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2Fj.febslet.2007.10.003","host_type":"publisher"},{"url":"https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/j.febslet.2007.10.003","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.febslet.2007.10.003","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/17950729","host_type":"repository"}],"fields_of_study":["Ion channel regulation and function","Nicotinic Acetylcholine Receptors Study","Neuroscience and Neuropharmacology Research"],"mesh_terms":["Disks Large Homolog 4 Protein","Amino Acid Sequence","Animals","Binding Sites","Brain","Cell Line","Female","Humans","Membrane Proteins","Oocytes","Recombinant Fusion Proteins","Xenopus","Sequence Homology, Amino Acid","Protein Structure, Tertiary","Receptors, Somatostatin","Intracellular Signaling Peptides and Proteins","Mice","Rats","In Vitro Techniques"],"keywords":["PDZ domain","Somatostatin","Somatostatin receptor","Receptor","Chemistry","Neuroscience","Cell biology","Internal medicine","Endocrinology","Biophysics","Biology","Biochemistry","Medicine"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T02:13:17.457258Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}