{"doi":"10.1016/j.etap.2014.09.011","title":"Determination of fluoroquinolones in chicken feces – A new liquid–liquid extraction method combined with LC–MS/MS","abstract":null,"journal":"Environmental Toxicology and Pharmacology","year":2014,"id":642220,"datarank":0.635115975689589,"base_score":4.23410650459726,"endowment":4.23410650459726,"self_citation_contribution":0.635115975689589,"citation_network_contribution":0.0,"self_endowment_contribution":0.635115975689589,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":68,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1670253,"name":"Gesine Scherz","orcid":null,"position":1,"is_corresponding":false},{"id":1670254,"name":"Siegrun A.I. Mohring","orcid":null,"position":2,"is_corresponding":false},{"id":1670255,"name":"Gerd Hamscher","orcid":null,"position":3,"is_corresponding":false},{"id":1670252,"name":"Franziska Janusch","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Determination of fluoroquinolones in chicken feces – A new liquid–liquid extraction method combined with LC–MS/MS","abstract":"The application of antibiotics including fluoroquinolones to farming animals is widespread and may lead to the development of antibiotic resistance and other environmental effects. To calculate environmental loads and for a proper risk assessment it is necessary to determine the antibiotic concentration in feces. Therefore, a new liquid-liquid extraction method combined with HPLC-MS/MS for the detection of marbofloxacin, ciprofloxacin, enrofloxacin and difloxacin in chicken feces was developed. Recoveries ranged from 51.0% to 83.5%. LOQs were between 0.10 and 1.09μg/kg. Feces of chickens treated with an enrofloxacin dosage of 10mg/kg bodyweight revealed maximum enrofloxacin and ciprofloxacin concentrations of 61.3 and 18.8mg/kg. Both antibiotics could be detected in feces up to two days after the last application in notable amounts (∼1mg/kg). Thus, feces of recently medicated chickens should not be used as a fertilizer without any further processing.","is_dataset_classified":null,"base_score":4.23410650459726,"endowment":4.23410650459726,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"25305740","pmcid":null,"openalex_id":"https://openalex.org/W1970162220","authors":[],"funders":[{"funder_name":"Deutsches Zentrum für Luft- und Raumfahrt","grant_id":"01KI1013A","title":null},{"funder_name":"Bundesministerium für Bildung und Forschung","grant_id":"","title":null}],"total_grants":2,"fwci":2.4688,"citation_percentile":0.8749342,"influential_citations":0,"citation_trend":[{"year":2015,"count":1},{"year":2016,"count":6},{"year":2017,"count":6},{"year":2018,"count":7},{"year":2019,"count":9},{"year":2020,"count":8},{"year":2021,"count":5},{"year":2022,"count":4},{"year":2023,"count":8},{"year":2024,"count":5},{"year":2025,"count":6},{"year":2026,"count":2}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S1382668914002191?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1382668914002191?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.etap.2014.09.011","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/25305740","host_type":"repository"}],"fields_of_study":["Pharmaceutical and Antibiotic Environmental Impacts","Antibiotics Pharmacokinetics and Efficacy","Pharmacological Effects and Assays","Animals","Anti-Bacterial Agents","Chickens","Chromatography, Liquid","Ciprofloxacin","Enrofloxacin","Environmental Monitoring","Feces","Fluoroquinolones","Liquid-Liquid Extraction","Solvents","Tandem Mass Spectrometry"],"mesh_terms":["Enrofloxacin","Animals","Anti-Bacterial Agents","Chickens","Chromatography, Liquid","Ciprofloxacin","Environmental Monitoring","Feces","Solvents","Fluoroquinolones","Tandem Mass Spectrometry","Liquid-Liquid Extraction"],"keywords":["Chromatography","Feces","Extraction (chemistry)","Liquid chromatography–mass spectrometry","Chemistry","Liquid–liquid extraction","Mass spectrometry","Biology","Microbiology","Chicken","Fluoroquinolones","Lc–ms/ms"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T21:59:03.058079Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}