{"doi":"10.1016/j.envres.2021.112472","title":"Association between exposure to air pollution and risk of allergic rhinitis: A systematic review and meta-analysis","abstract":null,"journal":"Environmental Research","year":2022,"id":638439,"datarank":0.7324202883879557,"base_score":4.882801922586371,"endowment":4.882801922586371,"self_citation_contribution":0.7324202883879557,"citation_network_contribution":0.0,"self_endowment_contribution":0.7324202883879557,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":131,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":246623,"name":"Wei Wu","orcid":"0000-0001-5164-2765","position":1,"is_corresponding":false},{"id":15748,"name":"Gang Wang","orcid":"0000-0001-7264-2457","position":2,"is_corresponding":false},{"id":817866,"name":"Xinyi Zhang","orcid":"0000-0003-4996-4698","position":3,"is_corresponding":false},{"id":192970,"name":"Qian Guo","orcid":null,"position":4,"is_corresponding":false},{"id":731703,"name":"Beibei Wang","orcid":"0000-0002-9581-2698","position":5,"is_corresponding":false},{"id":1658228,"name":"Suzhen Cao","orcid":null,"position":6,"is_corresponding":false},{"id":910609,"name":"Meilin Yan","orcid":null,"position":7,"is_corresponding":false},{"id":459932,"name":"Xiaochuan Pan","orcid":"0000-0002-3074-9771","position":8,"is_corresponding":false},{"id":657523,"name":"Tao Xue","orcid":"0000-0002-7045-2307","position":9,"is_corresponding":false},{"id":910026,"name":"Jicheng Gong","orcid":"0000-0003-1756-1763","position":10,"is_corresponding":false},{"id":1658232,"name":"Xiaoli Duan","orcid":"0000-0002-7424-9656","position":11,"is_corresponding":false},{"id":625808,"name":"Sai Li","orcid":"0000-0002-6362-3593","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Association between exposure to air pollution and risk of allergic rhinitis: A systematic review and meta-analysis","abstract":"<h4>Background</h4>Allergic rhinitis (AR) is one of the most common allergic diseases in the world, and usually persists throughout the activity. Epidemiological studies have shown a positive association between air pollution and allergic rhinitis. However, we could not find any meta-analysis of the risk of air pollutants (PM<sub>2.5</sub>, PM<sub>10</sub>, NO<sub>2</sub>, SO<sub>2</sub>, O<sub>3</sub> and CO) on the prevalence of AR in people of all ages.<h4>Objectives</h4>Carry out a meta-analysis on the results of recent studies (up to 2020) to present valid information about exposure to air pollution and risk of prevalence of AR.<h4>Methods</h4>We systematically searched three databases for studies up to December 17, 2020, including air pollution and AR. Random effect models were conducted to estimate the pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). Subgroup analysis, funnel plot, Egger's test, and the trim-and-fill method were also conducted.<h4>Results</h4>Thirty-five studies across 12 countries, including a total of 453,470 participants, were included. The OR per 10 μg/m<sup>3</sup> increase of pollutants was 1.13 (1.04-1.22) for PM<sub>10</sub> and 1.12 (1.05-1.20) for PM<sub>2.5</sub>. The OR per 10 μg/m<sup>3</sup> increment of gaseous pollutants were 1.13 (1.07-1.20) for NO<sub>2</sub>, 1.13 (1.04-1.22) for SO<sub>2</sub> and 1.07 (1.01-1.12) for O<sub>3</sub>. No significant association was observed between CO and AR. Children or adolescents are more sensitive to air pollution than adults. The effects of PM<sub>10</sub> and SO<sub>2</sub> were significantly stronger in Europe than Asia. The effects of air pollutants were more significant and higher in developing countries than in developed countries, except for PM<sub>10</sub>. A significant difference of subgroup test was found between developed and developing countries of NO<sub>2</sub>.<h4>Conclusion</h4>This meta-analysis showed a positive association between air pollution and the prevalence of allergic rhinitis, and identified geographic area and economic level as the potential modifiers for the association.","is_dataset_classified":null,"base_score":4.882801922586371,"endowment":4.882801922586371,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34863689","pmcid":null,"openalex_id":"https://openalex.org/W3216721301","authors":[],"funders":[{"funder_name":"Natural Science Foundation of Beijing Municipality","grant_id":"7202106","title":null}],"total_grants":1,"fwci":6.2725,"citation_percentile":0.98969072,"influential_citations":0,"citation_trend":[{"year":2022,"count":13},{"year":2023,"count":31},{"year":2024,"count":49},{"year":2025,"count":29},{"year":2026,"count":9}],"oa_status":"closed","license":"https://doi.org/10.15223/policy-004","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0013935121017734?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0013935121017734?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.envres.2021.112472","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34863689","host_type":"repository"}],"fields_of_study":["Allergic Rhinitis and Sensitization","Air Quality and Health Impacts","Asthma and respiratory diseases","Adolescent","Adult","Air Pollutants","Air Pollution","Child","Environmental Exposure","Humans","Particulate Matter","Rhinitis, Allergic"],"mesh_terms":["Adolescent","Adult","Air Pollutants","Air Pollution","Child","Environmental Exposure","Humans","Particulate Matter","Rhinitis, Allergic"],"keywords":["Funnel plot","Odds ratio","Meta-analysis","Publication bias","Air pollution","Confidence interval","Environmental health","Medicine","Air pollutants","Subgroup analysis","Epidemiology","Pollutant","Pollution","Demography","Internal medicine","Chemistry","Biology","Systematic review","allergic rhinitis"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T20:40:29.258700Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}