{"doi":"10.1016/j.envint.2022.107433","title":"Associations between airborne crude oil chemicals and symptom-based asthma","abstract":"RATIONALE: from burning/flaring oil and natural gas. Little is known about asthma risk among oil spill cleanup workers. OBJECTIVES: using data from the Gulf Long-Term Follow-up (GuLF) Study, a prospective cohort of 24,937 cleanup workers and 7,671 nonworkers following the DWH disaster. METHODS: used modeled estimates. We used modified Poisson regression to estimate risk ratios (RR) and 95% confidence intervals (CIs) for associations between spill-related exposures and asthma and a quantile-based g-computation approach to explore the joint effect of the BTEX-H mixture on asthma risk. RESULTS: OSRC workers had greater asthma risk than nonworkers (RR: 1.60, 95% CI: 1.38, 1.85). Higher estimated THC exposure levels were associated with increased risk in an exposure-dependent manner (linear trend test p < 0.0001). Asthma risk also increased with increasing exposure to individual BTEX-H chemicals and the chemical mixture: A simultaneous quartile increase in the BTEX-H mixture was associated with an increased asthma risk of 1.45 (95% CI: 1.35,1.55). With fewer cases, associations were less apparent for physician-diagnosed asthma alone. CONCLUSIONS: THC and BTEX-H were associated with increased asthma risk defined using wheeze symptoms as well as a physician diagnosis.","journal":"Environment International","year":2022,"id":250031,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":27,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9547,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":275136,"name":"Nicole M. Niehoff","orcid":"0000-0002-5852-3010","position":1,"is_corresponding":false},{"id":105707,"name":"Alexander P. Keil","orcid":"0000-0002-0955-6107","position":2,"is_corresponding":false},{"id":429851,"name":"William B. Jackson","orcid":"0000-0001-6672-0172","position":3,"is_corresponding":false},{"id":689916,"name":"Kate Christenbury","orcid":"0000-0003-1119-0236","position":4,"is_corresponding":false},{"id":338656,"name":"Patricia A. Stewart","orcid":null,"position":5,"is_corresponding":false},{"id":337994,"name":"Mark Stenzel","orcid":"0000-0001-7840-234X","position":6,"is_corresponding":false},{"id":361088,"name":"Tran Huynh","orcid":"0000-0002-1542-8582","position":7,"is_corresponding":false},{"id":337995,"name":"Caroline P. Groth","orcid":"0000-0001-9444-0207","position":8,"is_corresponding":false},{"id":361089,"name":"Gurumurthy Ramachandran","orcid":"0000-0001-9869-284X","position":9,"is_corresponding":false},{"id":337996,"name":"Sudipto Banerjee","orcid":"0000-0002-2239-208X","position":10,"is_corresponding":false},{"id":337993,"name":"Gregory C. Pratt","orcid":"0000-0003-0179-6314","position":11,"is_corresponding":false},{"id":388251,"name":"Matthew D. Curry","orcid":"0000-0003-3515-0191","position":12,"is_corresponding":false},{"id":330716,"name":"Lawrence S. Engel","orcid":"0000-0001-9268-4830","position":13,"is_corresponding":false},{"id":104612,"name":"Dale P. Sandler","orcid":"0000-0002-6776-0018","position":14,"is_corresponding":false},{"id":281523,"name":"Kaitlyn G. Lawrence","orcid":"0000-0002-8360-9326","position":0,"is_corresponding":true}],"reference_count":59,"raw_metadata":null,"created_at":"2026-07-19T00:24:28.242323Z","pmid":"35921771","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}