{"doi":"10.1016/j.envint.2021.106937","title":"Acute and longer-term cardiovascular conditions in the Deepwater Horizon Oil Spill Coast Guard Cohort","abstract":"INTRODUCTION: In 2010, the U.S. Coast Guard (USCG) led a clean-up response to the Deepwater Horizon (DWH) oil spill. Human studies evaluating acute and longer-term cardiovascular conditions associated with oil spill-related exposures are sparse. Thus, we aimed to investigate prevalent and incident cardiovascular symptoms/conditions in the DHW Oil Spill Coast Guard Cohort. METHODS: Self-reported oil spill exposures and cardiovascular symptoms were ascertained from post-deployment surveys (n = 4,885). For all active-duty cohort members (n = 45,193), prospective cardiovascular outcomes were classified via International Classification of Diseases, 9th Edition from military health encounter records up to 5.5 years post-DWH. We used log-binomial regression to calculate adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) in the cross-sectional analyses and Cox Proportional Hazards regression to calculate adjusted hazard ratios (aHR) and 95% CIs for incident cardiovascular diagnoses during 2010-2015 and stratifying by earlier (2010-2012) and later (2013-2015) time periods. RESULTS: = 2.72, 95% CI = 1.30-5.16, p-trend = 0.03). Similar associations were observed for sudden heartbeat changes and for being in the vicinity of burning oil exposure. In prospective analyses, responders (vs. non-responders) had an elevated risk for mitral valve disorders during 2013-2015 (aHR = 2.12, 95% CI = 1.15-3.90). Responders reporting ever (vs. never) crude oil inhalation exposure were at increased risk for essential hypertension, particularly benign essential hypertension during 2010-2012 (aHR = 2.00, 95% CI = 1.08-3.69). Responders with crude oil inhalation exposure also had an elevated risk for palpitations during 2013-2015 (aHR = 2.54, 95% CI = 1.36-4.74). Cardiovascular symptoms/conditions aPR and aHR estimates were generally stronger among responders reporting exposure to both crude oil and oil dispersants than among those reporting neither. CONCLUSIONS: In this large study of the DWH oil spill USCG responders, self-reported spill clean-up exposures were associated with acute and longer-term cardiovascular symptoms/conditions.","journal":"Environment International","year":2021,"id":165952,"datarank":1.2040910220069199,"base_score":3.58351893845611,"endowment":3.58351893845611,"self_citation_contribution":0.5375278407684165,"citation_network_contribution":0.6665631812385033,"self_endowment_contribution":0.5375278407684165,"citer_contribution":0.6665631812385033,"corpus_percentile":82.95041386245842,"corpus_rank":2205,"citation_count":35,"citer_count":26,"citers_with_citation_signal":18,"citers_with_endowment":18,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.5954,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":691505,"name":"Nicole Rowley","orcid":null,"position":1,"is_corresponding":false},{"id":314245,"name":"Mark C. Haigney","orcid":"0000-0001-6449-4386","position":2,"is_corresponding":false},{"id":689916,"name":"Kate Christenbury","orcid":"0000-0003-1119-0236","position":3,"is_corresponding":false},{"id":689915,"name":"J. Barrett","orcid":"0000-0002-7610-0505","position":4,"is_corresponding":false},{"id":689913,"name":"Dana L. Thomas","orcid":"0000-0003-2640-2297","position":5,"is_corresponding":false},{"id":330716,"name":"Lawrence S. Engel","orcid":"0000-0001-9268-4830","position":6,"is_corresponding":false},{"id":485025,"name":"Jennifer A. Rusiecki","orcid":"0000-0003-3881-8695","position":7,"is_corresponding":false},{"id":583704,"name":"Hristina Denic‐Roberts","orcid":"0000-0001-7068-1858","position":0,"is_corresponding":true}],"reference_count":59,"raw_metadata":null,"created_at":"2026-07-18T23:45:45.220559Z","pmid":"34688052","pmcid":"PMC8688193","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}