{"doi":"10.1016/j.ejim.2023.01.019","title":"Comparison of missed adenomas in deep-sedated and unsedated colonoscopy: A multicenter retrospective study","abstract":null,"journal":"European Journal of Internal Medicine","year":2023,"id":597899,"datarank":0.26876392038420827,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.0,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1531859,"name":"Yanhua Zheng","orcid":"0000-0001-7980-122X","position":1,"is_corresponding":false},{"id":675568,"name":"Qing Wang","orcid":"0000-0002-6603-3134","position":2,"is_corresponding":false},{"id":1531860,"name":"Jieping Lv","orcid":null,"position":3,"is_corresponding":false},{"id":1060962,"name":"Hongjin Wang","orcid":null,"position":4,"is_corresponding":false},{"id":794045,"name":"Qing Wen","orcid":"0000-0001-9392-068X","position":5,"is_corresponding":false},{"id":313654,"name":"Zhenzhen Wang","orcid":"0000-0001-6961-4367","position":6,"is_corresponding":false},{"id":1531865,"name":"Guanfeng Wang","orcid":null,"position":7,"is_corresponding":false},{"id":77660,"name":"Hui Jia","orcid":"0000-0001-7352-4698","position":8,"is_corresponding":false},{"id":1531867,"name":"Fengzhen Cao","orcid":null,"position":9,"is_corresponding":false},{"id":1531869,"name":"Naping Wang","orcid":null,"position":10,"is_corresponding":false},{"id":1531871,"name":"Junlian Hao","orcid":null,"position":11,"is_corresponding":false},{"id":1293536,"name":"Yiping Zhang","orcid":"0009-0005-0465-7629","position":12,"is_corresponding":false},{"id":303508,"name":"Xiaopeng Wu","orcid":null,"position":13,"is_corresponding":false},{"id":1003043,"name":"Haihua Chen","orcid":"0000-0002-7088-9752","position":14,"is_corresponding":false},{"id":1531872,"name":"Junhui Lu","orcid":null,"position":15,"is_corresponding":false},{"id":493723,"name":"Xing Chen","orcid":"0000-0001-7084-3052","position":16,"is_corresponding":false},{"id":1531858,"name":"Yue Sui","orcid":"0000-0003-0108-1503","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Comparison of missed adenomas in deep-sedated and unsedated colonoscopy: A multicenter retrospective study","abstract":"<h4>Background</h4>Deep-sedated colonoscopy with propofol is widely used in China. However, its impact on quality metrics remains controversial. We aimed to investigate the effects of deep-sedated colonoscopy on missed adenomas, specifically in each colorectal segment.<h4>Methods</h4>Data of 3710 individuals from seven hospitals in China who underwent an initial colonoscopy with or without propofol sedation and a second colonoscopy without sedation within six months for surveillance or polypectomy by endoscopist of the same level between October 2020 and September 2021 were retrospectively analyzed.<h4>Results</h4>A total of 1113 missed adenomas in 3710 patients were evaluated. The adenoma miss rate (AMR) was significantly higher in deep-sedated colonoscopy than in unsedated colonoscop [19.14% (578/3020) vs. 16.15% (535/3313), P < 0.05]. The risk of missing adenomas in deep-sedated colonoscopy was 1.229 times higher than in unsedated colonoscopy (OR, 1.229; 95% CI: 1.080-1.399). AMRs of the splenic flexure (26.02% [96/369] vs. 16.04% [47/293], P < 0.05) and descending colon (20.86% [102/489] vs. 13.37% [54/404], P < 0.05) were significantly higher in deep-sedated colonoscopy than in unsedated colonoscopy when performed by middle-level endoscopists rather than high-level endoscopists (P < 0.05).<h4>Conclusions</h4>AMR was higher in deep-sedated colonoscopy than in unsedated colonoscopy. Furthermore, adenomas in the splenic flexure and descending colon were more frequently missed in deep-sedated colonoscopy than in unsedated colonoscopy, particularly when performed by less experienced endoscopists.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36710136","pmcid":null,"openalex_id":null,"authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":null,"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0953620523000237?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0953620523000237?httpAccept=text/plain","host_type":"publisher"}],"fields_of_study":[],"mesh_terms":["Humans","Adenoma","Colorectal Neoplasms","Propofol","Colonoscopy","Retrospective Studies","Time Factors"],"keywords":["Sedation","Adenoma","Colonoscopy","Colorectal Cancer","Miss Rate"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T14:33:14.025675Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}