{"doi":"10.1016/j.drudis.2025.104362","title":"Advances in artificial intelligence-envisioned technologies for protein and nucleic acid research","abstract":null,"journal":"Drug Discovery Today","year":2025,"id":643254,"datarank":0.3453877639491069,"base_score":2.302585092994046,"endowment":2.302585092994046,"self_citation_contribution":0.3453877639491069,"citation_network_contribution":0.0,"self_endowment_contribution":0.3453877639491069,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1673564,"name":"Abdelwahab Omri","orcid":null,"position":1,"is_corresponding":false},{"id":1673563,"name":"Amol D. Gholap","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Advances in artificial intelligence-envisioned technologies for protein and nucleic acid research","abstract":"Artificial intelligence (AI) and machine learning (ML) have revolutionized pharmaceutical research, particularly in protein and nucleic acid studies. This review summarizes the current status of AI and ML applications in the pharmaceutical sector, focusing on innovative tools, web servers, and databases. This paper highlights how these technologies address key challenges in drug development including high costs, lengthy timelines, and the complexity of biological systems. Furthermore, the potential of AI in personalized medicine, cancer drug response prediction, and biomarker identification is discussed. The integration of AI and ML in pharmaceutical research promises to accelerate drug discovery, reduce development costs, and ultimately lead to more effective and personalized therapeutic strategies.","is_dataset_classified":null,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"40252991","pmcid":null,"openalex_id":"https://openalex.org/W4409538420","authors":[],"funders":[],"total_grants":0,"fwci":3.4793,"citation_percentile":0.9284311,"influential_citations":0,"citation_trend":[{"year":2025,"count":6},{"year":2026,"count":2}],"oa_status":"hybrid","license":"cc-by-nc-nd","oa_locations":[{"url":"https://doi.org/10.1016/j.drudis.2025.104362","host_type":"journal"},{"url":"https://doi.org/10.1016/j.drudis.2025.104362","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1359644625000753?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1359644625000753?httpAccept=text/plain","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/40252991","host_type":"repository"}],"fields_of_study":["Genetics, Bioinformatics, and Biomedical Research","Machine Learning in Bioinformatics","Gene expression and cancer classification","Artificial Intelligence","Humans","Nucleic Acids","Precision Medicine","Machine Learning","Proteins","Drug Discovery","Drug Development","Animals"],"mesh_terms":["Machine Learning","Drug Development","Animals","Artificial Intelligence","Humans","Nucleic Acids","Proteins","Drug Discovery","Precision Medicine"],"keywords":["Nucleic acid","Computational biology","Computer science","Artificial intelligence","Chemistry","Nanotechnology","Biology","Biochemistry","Materials science","algorithms","machine learning","peptide","personalized medicine","protein","tools"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T14:41:41.451387Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}