{"doi":"10.1016/j.dadr.2024.100278","title":"High-risk use of prescription opioids among patients treated for alcohol problems in New York State. A repeated cross-sectional study, 2005–2018","abstract":"Patients with alcohol use disorder (AUD) and high-risk opioid use are at risk of serious complications. The purpose of this study was to estimate the prevalence of and factors associated with high-risk opioid use in patients with an alcohol use problem from 2005 to 2018. This repeated cross-sectional study analyzed data from first admissions for alcohol treatment (2005–2018) to the NYS Office of Addiction Services and Supports merged with Medicaid Claims Data. High-risk opioid use was defined as opioid dose ≥50 morphine mg equivalents (MME) per day; opioid prescriptions overlapping ≥7 days; opioids for chronic pain >90 days or opioids for acute pain >7 days. Patients receiving ≥50 MME increased from 690 to 3226 from 2005 to 2010; then decreased to 2330 in 2018. From 2005–2011, patients with opioid prescriptions overlapping ≥7 days increased from 226 to 1594 then decreased to 892 in 2018. From 2005–2010, opioid use >7 days for acute pain increased from 133 to 970 and plateaued after 2010. From 2005–2018, patients who received opioids >90 days for chronic pain trended from 186 to 1655. White patients, females, age 36–55, patients with chronic and acute pain diagnoses had the highest rates of high-risk use. The prevalence of high-risk opioid use in patients with alcohol use problems increased from 2005 to 2011, and generally decreased after 2010. However, prevalence of opioids >90 days for chronic pain trended up from 2005 to 2018. High-risk opioid use among patients with AUD emphasizes the need to develop interventional strategies to improve patient care. • Examined trends in high-risk opioid use in patients with alcohol use problems. • High-dose opioid usage peaked in 2010 during the study period (2005–2018). • The trend of opioid use >90 days for chronic pain increased from 2005 to 2018; opioid use >7 days for acute pain plateaued after 2010. • Most commonly used opioid was oxycodone for all predefined high-risk use indicators. • Patients with chronic and acute pain had the highest rates of high-risk opioid use.","journal":"Drug and Alcohol Dependence Reports","year":2024,"id":471734,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.747,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":700451,"name":"Chi‐Hua Lu","orcid":"0000-0001-9647-4363","position":1,"is_corresponding":false},{"id":480751,"name":"Zackary Falls","orcid":"0000-0003-4116-0441","position":2,"is_corresponding":false},{"id":1126553,"name":"Gail Jette","orcid":null,"position":3,"is_corresponding":false},{"id":1126554,"name":"Walter Gibson","orcid":null,"position":4,"is_corresponding":false},{"id":545624,"name":"Peter L. Elkin","orcid":"0000-0001-9616-6811","position":5,"is_corresponding":false},{"id":423881,"name":"Kenneth E. Leonard","orcid":"0000-0001-6658-1264","position":6,"is_corresponding":false},{"id":700452,"name":"Edward M. Bednarczyk","orcid":"0000-0001-7918-9317","position":7,"is_corresponding":false},{"id":351344,"name":"David M. Jacobs","orcid":"0000-0001-9240-7067","position":8,"is_corresponding":false},{"id":1126555,"name":"Tzu‐Yin Kuo","orcid":null,"position":0,"is_corresponding":true}],"reference_count":49,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:05:48.788780Z","pmid":"39286536","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}