{"doi":"10.1016/j.dadr.2023.100213","title":"Pilot study of a community pharmacist led program to treat hepatitis C virus among people who inject drugs","abstract":"Background: People who inject drugs (PWID) are a key population for treatment with direct-acting antiviral medications (DAAs) to eliminate hepatitis C virus (HCV). We developed a Pharmacist, Physician, and Patient Navigator Collaborative Care Model (PPP-CCM) for delivery of HCV treatment; this study describes clinical outcomes related to HCV treatment (initial evaluation, treatment initiation, completion, and cure), as well as patient satisfaction. Methods: We conducted a single-arm prospective pilot study of adult PWID living with HCV. Participants completed baseline and six-month follow-up surveys, and treatment and outcomes were abstracted from electronic health records. Primary outcome was linkage to pharmacist for HCV evaluation; secondary outcomes included DAA initiation, completion, and cure, as well as patient-reported satisfaction. Results: Of the 40 PWID enrolled, mean age was 43.6 years, 12 (30 %) were female, 20 (50 %) were non-white, and 15 (38 %) were unhoused. Thirty-eight (95 %) were successfully linked to the pharmacist for initial evaluation. Of those, 21/38 (55 %) initiated DAAs, and 16/21 (76 %) completed treatment. Among those completing treatment who had viral load data to document whether they achieved \"sustained virologic response\", i.e. cure, 10/11 (91 %) were found to be cured. There was high satisfaction with 100 % responding \"agree or strongly agree\" that they had a positive experience with the pharmacist. Conclusion: Nearly all participants in this pilot were successfully linked to the pharmacist for evaluation, and more than half were started on DAAs; results provide preliminary evidence of feasibility of pharmacist-led models of HCV treatment for PWID. Clinicaltrialsgov registration number: NCT04698629.","journal":"Drug and Alcohol Dependence Reports","year":2023,"id":343750,"datarank":0.6933428249017395,"base_score":2.70805020110221,"endowment":2.70805020110221,"self_citation_contribution":0.40620753016533157,"citation_network_contribution":0.287135294736408,"self_endowment_contribution":0.40620753016533157,"citer_contribution":0.287135294736408,"corpus_percentile":null,"corpus_rank":null,"citation_count":14,"citer_count":12,"citers_with_citation_signal":7,"citers_with_endowment":7,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.958,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT04698629"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1082218,"name":"Alex J. Gojic","orcid":null,"position":1,"is_corresponding":false},{"id":6943,"name":"Kerry A. Pierce","orcid":"0000-0001-8078-640X","position":2,"is_corresponding":false},{"id":697688,"name":"Elizabeth L. Tung","orcid":"0000-0001-6898-1106","position":3,"is_corresponding":false},{"id":1082219,"name":"N. Connolly","orcid":null,"position":4,"is_corresponding":false},{"id":1082220,"name":"A.C. Radick","orcid":null,"position":5,"is_corresponding":false},{"id":1082221,"name":"Rameck Hunt","orcid":null,"position":6,"is_corresponding":false},{"id":1082222,"name":"Russell Sandvold","orcid":null,"position":7,"is_corresponding":false},{"id":1081787,"name":"Katherine Johansen Taber","orcid":"0000-0003-3051-2667","position":8,"is_corresponding":false},{"id":668118,"name":"Michael Ninburg","orcid":"0000-0001-8592-5878","position":9,"is_corresponding":false},{"id":1082223,"name":"R.H. Kubiniec","orcid":null,"position":10,"is_corresponding":false},{"id":1082224,"name":"J.D. Scott","orcid":null,"position":11,"is_corresponding":false},{"id":1082225,"name":"RN Hansen","orcid":null,"position":12,"is_corresponding":false},{"id":331653,"name":"Joanne D. Stekler","orcid":"0000-0001-8064-3011","position":13,"is_corresponding":false},{"id":668116,"name":"Elizabeth J. Austin","orcid":"0000-0002-4221-1362","position":14,"is_corresponding":false},{"id":1082226,"name":"E.C. Williams","orcid":null,"position":15,"is_corresponding":false},{"id":1082227,"name":"S N Glick","orcid":null,"position":16,"is_corresponding":false},{"id":1082217,"name":"J.I. Tsui","orcid":null,"position":0,"is_corresponding":true}],"reference_count":54,"raw_metadata":null,"created_at":"2026-07-19T01:11:26.556051Z","pmid":"38261893","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}