{"doi":"10.1016/j.cub.2020.10.091","title":"Theta, but Not Gamma Oscillations in Area V4 Depend on Input from Primary Visual Cortex","abstract":"Here, we report on experiments in macaque monkeys in which we experimentally assessed the presence of both oscillations in the neural activity recorded from multi-electrode arrays in V1 and V4 before and after a permanent V1 lesion. With intact cortex, theta and gamma oscillations could be reliably elicited in V1 and V4 when monkeys viewed a visual contour illusion and showed phase-to-amplitude coupling. Laminar analysis in V1 revealed that both theta and gamma oscillations occurred primarily in the supragranular layers, the cortical output compartment of V1. However, there was a clear dissociation between the two rhythms in V4 that became apparent when the major feedforward input to V4 was removed by lesioning V1: although V1 lesioning eliminated V4 theta, it had little effect on V4 gamma power except for delaying its emergence by >100 ms. These findings suggest that theta is more tightly associated with feedforward processing than gamma and pose limits on the proposed role of gamma as a feedforward mechanism.","journal":"Current Biology","year":2020,"id":100347,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":29,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9443,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":492613,"name":"Michele A. Cox","orcid":"0000-0002-6822-6503","position":1,"is_corresponding":false},{"id":492614,"name":"Kacie Dougherty","orcid":"0000-0001-6295-0026","position":2,"is_corresponding":false},{"id":266433,"name":"Richard C. Saunders","orcid":"0000-0001-8221-6988","position":3,"is_corresponding":false},{"id":492615,"name":"Joscha T. Schmiedt","orcid":"0000-0001-6233-1866","position":4,"is_corresponding":false},{"id":259028,"name":"David A. Leopold","orcid":"0000-0002-1345-6360","position":5,"is_corresponding":false},{"id":490923,"name":"Alexander Maier","orcid":"0000-0002-7250-502X","position":6,"is_corresponding":false},{"id":266435,"name":"Michael C. Schmid","orcid":"0000-0003-1424-130X","position":7,"is_corresponding":false},{"id":492612,"name":"Ricardo Kienitz","orcid":"0000-0003-2328-3413","position":0,"is_corresponding":true}],"reference_count":63,"raw_metadata":null,"created_at":"2026-07-18T22:38:35.493878Z","pmid":"33278356","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}