{"doi":"10.1016/j.cub.2013.04.048","title":"Phyllotaxis and Rhizotaxis in Arabidopsis Are Modified by Three PLETHORA Transcription Factors","abstract":null,"journal":"Current Biology","year":2013,"id":597810,"datarank":0.7346759699926367,"base_score":4.897839799950911,"endowment":4.897839799950911,"self_citation_contribution":0.7346759699926367,"citation_network_contribution":0.0,"self_endowment_contribution":0.7346759699926367,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":133,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1531576,"name":"Marta Laskowski","orcid":null,"position":1,"is_corresponding":false},{"id":1531577,"name":"Yujuan Du","orcid":null,"position":2,"is_corresponding":false},{"id":1531578,"name":"Kalika Prasad","orcid":null,"position":3,"is_corresponding":false},{"id":1531579,"name":"Stephen Grigg","orcid":null,"position":4,"is_corresponding":false},{"id":1531580,"name":"Violaine Pinon","orcid":null,"position":5,"is_corresponding":false},{"id":632892,"name":"Ben Scheres","orcid":"0000-0001-5400-9578","position":6,"is_corresponding":false},{"id":1531575,"name":"Hugo Hofhuis","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Phyllotaxis and Rhizotaxis in Arabidopsis Are Modified by Three PLETHORA Transcription Factors","abstract":"<h4>Background</h4>The juxtaposition of newly formed primordia in the root and shoot differs greatly, but their formation in both contexts depends on local accumulation of the signaling molecule auxin. Whether the spacing of lateral roots along the main root and the arrangement of leaf primordia at the plant apex are controlled by related underlying mechanisms has remained unclear.<h4>Results</h4>Here, we show that, in Arabidopsis thaliana, three transcriptional regulators implicated in phyllotaxis, PLETHORA3 (PLT3), PLT5, and PLT7, are expressed in incipient lateral root primordia where they are required for primordium development and lateral root emergence. Furthermore, all three PLT proteins prevent the formation of primordia close to one another, because, in their absence, successive lateral root primordia are frequently grouped in close longitudinal or radial clusters. The triple plt mutant phenotype is rescued by PLT-vYFP fusion proteins, which are expressed in the shoot meristem as well as the root, but not by expression of PLT7 in the shoot alone. Expression of all three PLT genes requires auxin response factors ARF7 and ARF19, and the reintroduction of PLT activity suffices to rescue lateral root formation in arf7,arf19.<h4>Conclusions</h4>Intriguingly PLT 3, PLT5, and PLT7 not only control the positioning of organs at the shoot meristem but also in the root; a striking observation that raises many evolutionary questions.","is_dataset_classified":null,"base_score":4.897839799950911,"endowment":4.897839799950911,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23684976","pmcid":null,"openalex_id":"https://openalex.org/W2163924155","authors":[],"funders":[{"funder_name":"European Commission","grant_id":"232914","title":"Systems Biology to understand Plant Architecture"},{"funder_name":"National Science Foundation","grant_id":"0950866","title":"RUI: Lateral Root Initiation"},{"funder_name":"European Commission","grant_id":"275726","title":"A conserved mechanism regulating shoot and root lateral organ placement"}],"total_grants":3,"fwci":12.4215,"citation_percentile":0.98606953,"influential_citations":0,"citation_trend":[{"year":2013,"count":5},{"year":2014,"count":8},{"year":2015,"count":9},{"year":2016,"count":7},{"year":2017,"count":10},{"year":2018,"count":6},{"year":2019,"count":9},{"year":2020,"count":10},{"year":2021,"count":10},{"year":2022,"count":16},{"year":2023,"count":9},{"year":2024,"count":17},{"year":2025,"count":9},{"year":2026,"count":8}],"oa_status":"bronze","license":"Elsevier Non-Commercial","oa_locations":[{"url":"http://www.cell.com/article/S0960982213004892/pdf","host_type":"journal"},{"url":"http://www.cell.com/article/S0960982213004892/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0960982213004892?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0960982213004892?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.cub.2013.04.048","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23684976","host_type":"repository"},{"url":"https://orca.cardiff.ac.uk/id/eprint/57677/","host_type":"repository"},{"url":"https://research.wur.nl/en/publications/phyllotaxis-and-rhizotaxis-in-arabidopsis-are-modified-by-three-p","host_type":"repository"},{"url":"http://dx.doi.org/10.1016/j.cub.2013.04.048","host_type":""},{"url":"https://dx.doi.org/10.1016/j.cub.2013.04.048","host_type":""}],"fields_of_study":["Plant Molecular Biology Research","Polysaccharides and Plant Cell Walls","Plant Gene Expression Analysis","0301 basic medicine","0303 health sciences","03 medical and health sciences","Arabidopsis","Arabidopsis Proteins","Gene Expression Regulation, Plant","Meristem","Plant Leaves","Plant Roots","Transcription Factors"],"mesh_terms":["Transcription Factors","Arabidopsis","Gene Expression Regulation, Plant","Plant Leaves","Plant Roots","Meristem","Arabidopsis Proteins"],"keywords":["Biology","Phyllotaxis","Arabidopsis","Transcription factor","Transcription (linguistics)","Computational biology","Genetics","Gene","Meristem","Agricultural and Biological Sciences(all)","Biochemistry, Genetics and Molecular Biology(all)","Arabidopsis Proteins","growth","auxin transport","system","Plant Roots","arf19","lateral root initiation","proteins","Plant Leaves","Gene Expression Regulation, Plant","expression","thaliana","nph4/arf7","Transcription Factors"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T14:18:21.349941Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}