{"doi":"10.1016/j.clinph.2018.10.016","title":"Simultaneously recorded intracranial and scalp high frequency oscillations help identify patients with poor postsurgical seizure outcome","abstract":null,"journal":"Clinical Neurophysiology","year":2019,"id":653630,"datarank":0.5244761342199721,"base_score":3.4965075614664802,"endowment":3.4965075614664802,"self_citation_contribution":0.5244761342199721,"citation_network_contribution":0.0,"self_endowment_contribution":0.5244761342199721,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":32,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1705448,"name":"C. Klus","orcid":null,"position":1,"is_corresponding":false},{"id":1705449,"name":"M. Dümpelmann","orcid":null,"position":2,"is_corresponding":false},{"id":1705450,"name":"A. Schulze-Bonhage","orcid":null,"position":3,"is_corresponding":false},{"id":1032976,"name":"J. Jacobs","orcid":"0000-0003-2913-6297","position":4,"is_corresponding":false},{"id":1705447,"name":"N. Kuhnke","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Simultaneously recorded intracranial and scalp high frequency oscillations help identify patients with poor postsurgical seizure outcome","abstract":"<h4>Objective</h4>High frequency oscillations (HFO) between 80-500 Hz are markers of epileptic areas in intracranial and maybe also scalp EEG. We investigate simultaneous recordings of scalp and intracranial EEG and hypothesize that scalp HFOs provide important additional clinical information in the presurgical setting.<h4>Methods</h4>Spikes and HFOs were visually identified in all intracranial scalp EEG channels. Analysis of correlation of event location between intracranial and scalp EEG as well as relationship between events and the SOZ and zone of surgical removal was performed.<h4>Results</h4>24 patients could be included, 23 showed spikes and 19 HFOs on scalp recordings. In 15/19 patients highest scalp HFO rate was located over the implantation side, with 13 patients having the highest scalp and intracranial HFO rate over the same region. 17 patients underwent surgery, 7 became seizure free. Patients with poor post-operative outcome showed significantly more regions with HFO than those with seizure free outcome.<h4>Conclusions</h4>Scalp HFOs are mostly located over the SOZ. Widespread scalp HFOs are indicative of a larger epileptic network and associated with poor postsurgical outcome.<h4>Significance</h4>Analysis of scalp HFO add clinically important information about the extent of epileptic areas during presurgical simultaneous scalp and intracranial EEG recordings.","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30529879","pmcid":null,"openalex_id":"https://openalex.org/W2903372140","authors":[],"funders":[{"funder_name":"German Research Foundation","grant_id":"JA1725/2-1","title":null},{"funder_name":"Deutsche Forschungsgemeinschaft","grant_id":"unidentified","title":"unidentified"}],"total_grants":2,"fwci":1.9612,"citation_percentile":0.86929084,"influential_citations":0,"citation_trend":[{"year":2019,"count":4},{"year":2020,"count":5},{"year":2021,"count":4},{"year":2022,"count":4},{"year":2023,"count":1},{"year":2024,"count":6},{"year":2025,"count":2},{"year":2026,"count":5}],"oa_status":"closed","license":"Elsevier TDM","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S1388245718313713?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1388245718313713?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.clinph.2018.10.016","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/30529879","host_type":"repository"},{"url":"https://dx.doi.org/10.1016/j.clinph.2018.10.016","host_type":""},{"url":"https://doi.org/https://doi.org/10.1016/j.clinph.2018.10.016","host_type":""}],"fields_of_study":["Epilepsy research and treatment","Cerebrospinal fluid and hydrocephalus","Anesthesia and Sedative Agents","03 medical and health sciences","0302 clinical medicine","Adolescent","Adult","Cohort Studies","Electrocorticography","Electroencephalography","Epilepsy","Female","Humans","Male","Middle Aged","Postoperative Complications","Scalp","Seizures"],"mesh_terms":["Electrocorticography","Adolescent","Adult","Electroencephalography","Epilepsy","Female","Humans","Male","Middle Aged","Postoperative Complications","Scalp","Seizures","Cohort Studies"],"keywords":["Scalp","Medicine","Outcome (game theory)","Anesthesia","Audiology","Surgery","Mathematics","Epilepsy Surgery","refractory epilepsy","Spikes","High Frequency Oscillations","Seizure Onset","Adult","Male","Epilepsy","Adolescent","610","Electroencephalography","Epilepsie","Middle Aged","Cohort Studies","Postoperative Complications","Seizures","Humans","Female","Electrocorticography"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"No poverty"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T23:25:52.663148Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}