{"doi":"10.1016/j.clinbiochem.2011.08.1133","title":"Prooxidant–anti-oxidant balance is not associated with extent of coronary artery disease","abstract":null,"journal":"Clinical Biochemistry","year":2011,"id":640756,"datarank":0.44166584687496613,"base_score":2.9444389791664403,"endowment":2.9444389791664403,"self_citation_contribution":0.44166584687496613,"citation_network_contribution":0.0,"self_endowment_contribution":0.44166584687496613,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":18,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":637782,"name":"Hossein Pourghadamyari","orcid":"0000-0002-4969-8572","position":1,"is_corresponding":false},{"id":1665460,"name":"Mohsen Moohebati","orcid":null,"position":2,"is_corresponding":false},{"id":1665461,"name":"Seyyed Mohammad Reza Parizadeh","orcid":null,"position":3,"is_corresponding":false},{"id":1665462,"name":"Shima Tavallaie","orcid":null,"position":4,"is_corresponding":false},{"id":1665463,"name":"Roghayeh Paydar","orcid":null,"position":5,"is_corresponding":false},{"id":1665464,"name":"Homa Falsoleiman","orcid":null,"position":6,"is_corresponding":false},{"id":1665465,"name":"Mashalla Dehghani","orcid":null,"position":7,"is_corresponding":false},{"id":1665466,"name":"Afsoon Fazlinezhad","orcid":null,"position":8,"is_corresponding":false},{"id":1665467,"name":"Maral Amini","orcid":null,"position":9,"is_corresponding":false},{"id":1665468,"name":"Fatemeh Khorashadizadeh","orcid":null,"position":10,"is_corresponding":false},{"id":1665469,"name":"Majid Ghayour-Mobarhan","orcid":null,"position":11,"is_corresponding":false},{"id":1665470,"name":"Gordon A. Ferns","orcid":null,"position":12,"is_corresponding":false},{"id":374724,"name":"Amir Ali Rahsepar","orcid":"0000-0002-6228-4673","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Prooxidant–anti-oxidant balance is not associated with extent of coronary artery disease","abstract":"<h4>Objective</h4>We have measured the pro-oxidant-antioxidant-balance (PAB) levels in patients with defined coronary artery disease (CAD) and compared them with concentrations in healthy subjects.<h4>Design and methods</h4>Based on angiography results, 400 patients with stable CAD were divided into CAD- and CAD+, this being further subcategorized into groups with single-, double- and triple-vessel disease (VD).<h4>Results</h4>The mean PAB values in the healthy subjects, was significantly lower than for other groups (P<0.001). In CAD- patients, PAB levels were 123.2 ± 43.9, which was not statistically different compared to groups with SVD, 2VD and 3VD (P>0.05). In the CAD+ group, PAB values in 1VD, 2VD and 3VD were not significantly different among patients with SVD, 2VD and 3VD (P>0.05).<h4>Conclusions</h4>In conclusion, we found higher levels of oxidative stress in CAD+ patients compared to healthy subjects. The oxidation level was not related to measures of the extent of CAD such as number of stenosed vessels.","is_dataset_classified":null,"base_score":2.9444389791664403,"endowment":2.9444389791664403,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21889931","pmcid":null,"openalex_id":"https://openalex.org/W2032197509","authors":[],"funders":[{"funder_name":"Mashhad University of Medical Sciences","grant_id":"","title":null}],"total_grants":1,"fwci":1.0901,"citation_percentile":0.7418717,"influential_citations":0,"citation_trend":[{"year":2012,"count":1},{"year":2013,"count":5},{"year":2015,"count":3},{"year":2016,"count":1},{"year":2017,"count":1},{"year":2018,"count":3},{"year":2020,"count":1},{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":1}],"oa_status":"green","license":"cc-by","oa_locations":[{"url":"https://figshare.com/articles/journal_contribution/Prooxidant-anti-oxidant_balance_is_not_associated_with_extent_of_coronary_artery_disease/23391692","host_type":"repository"},{"url":"https://figshare.com/articles/journal_contribution/Prooxidant-anti-oxidant_balance_is_not_associated_with_extent_of_coronary_artery_disease/23391692","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S0009912011025951?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0009912011025951?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.clinbiochem.2011.08.1133","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21889931","host_type":"repository"},{"url":"http://sro.sussex.ac.uk/id/eprint/42644/","host_type":"repository"}],"fields_of_study":["Paraoxonase enzyme and polymorphisms","Antioxidant Activity and Oxidative Stress","Cardiovascular Health and Disease Prevention","Antioxidants","Case-Control Studies","Coronary Angiography","Coronary Artery Disease","Female","Humans","Male","Middle Aged","Oxidative Stress","Reactive Oxygen Species"],"mesh_terms":["Antioxidants","Coronary Artery Disease","Female","Humans","Male","Middle Aged","Case-Control Studies","Coronary Angiography","Reactive Oxygen Species","Oxidative Stress"],"keywords":["Coronary artery disease","Medicine","Internal medicine","Oxidative stress","CAD","Cardiology","Coronary angiography","Antioxidant","Antioxidant capacity","Artery","Gastroenterology","Myocardial infarction","Biochemistry","Biology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T13:42:11.679989Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}