{"doi":"10.1016/j.clbc.2024.05.009","title":"New Strategy for Breast Cancer Related Lymphedema Treatment by Endermology: ELOCS Phase II Randomized Controlled Trial","abstract":null,"journal":"Clinical Breast Cancer","year":2024,"id":617452,"datarank":0.3099500710120395,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0685343841469244,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0685343841469244,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":3,"citers_with_citation_signal":3,"citers_with_endowment":3,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1592383,"name":"Ariane Weyl","orcid":"0000-0002-6128-9181","position":1,"is_corresponding":false},{"id":1592385,"name":"Clara Brusq","orcid":null,"position":2,"is_corresponding":false},{"id":1592387,"name":"Benoît Chaput","orcid":null,"position":3,"is_corresponding":false},{"id":1587332,"name":"Barbara Garmy-Susini","orcid":"0000-0001-6100-2294","position":4,"is_corresponding":false},{"id":38523,"name":"Vanina Bongard","orcid":"0000-0001-5789-0815","position":5,"is_corresponding":false},{"id":1592390,"name":"Charlotte Vaysse","orcid":null,"position":6,"is_corresponding":false},{"id":1592381,"name":"Julie Malloizel-Delaunay","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"New Strategy for Breast Cancer Related Lymphedema Treatment by Endermology: ELOCS Phase II Randomized Controlled Trial.","abstract":"<h4>Background</h4>This phase II trial sought to be the first of its kind to estimate the success rate of endermology in reducing breast cancer-related lymphedema.<h4>Patients and methods</h4>ELOCS is a French, monocentric, randomized, open-label phase II trial. Patients were randomized to receive the following over a 5-day treatment period: standard intensive decongestant treatment (IDT) (bandages and manual lymphatic drainage MLD) (group 1); IDT including bandages, MLD, and Cellu M6 (group 2); and IDT including bandages and Cellu M6 (Group 3). The main endpoint was the success rate in each group, (reduction of at least 30% in the excess volume). We estimated that endermology treatment (groups 2 and 3) would be of interest successes occurred in at least 21 out of 31 patients.<h4>Results</h4>A total of 93 patients were included (31 patients in each of the 3 groups). The median age was 64.5 years (IQR: [56.4-71.3]). Patients were treated with mastectomy (n = 35), axillary lymphadenectomy (n = 80), radiotherapy (n = 91), and chemotherapy (n = 68). The mean relative reduction in excess volume was 38% in group 1, 33% in group 2, and 34% in group 3. Success rate was 58.1% in group 1 (18/31, P = ,0237), 51.6% (16/31, P = ,5) in group 2, and 64.5% (20/31, P = ,075) in group 3. In the LPG groups (2 and 3), 10/62 (16%) patients found LPG painful and 9/62 (15%) patients considered it to be unpleasant.<h4>Conclusion</h4>Even though the critical threshold of 21 successes was not met, this study was the first to validate a standardized and reproducible endermology protocol.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"38853038","pmcid":null,"openalex_id":null,"authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[],"fields_of_study":[],"mesh_terms":["Humans","Breast Neoplasms","Lymphedema","Treatment Outcome","Lymph Node Excision","Mastectomy","Bandages","Aged","Middle Aged","Female","Breast Cancer Lymphedema","Manual Lymphatic Drainage"],"keywords":["Supportive Care","Breast Cancer-related Lymphedema","Lymphology","Endermology","Intensive Decongestive Treatment"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-03T01:44:41.636608Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}