{"doi":"10.1016/j.chom.2008.08.010","title":"Malaria Parasite Pre-Erythrocytic Stage Infection: Gliding and Hiding","abstract":null,"journal":"Cell Host &amp; Microbe","year":2008,"id":633557,"datarank":0.7401710899696038,"base_score":4.9344739331306915,"endowment":4.9344739331306915,"self_citation_contribution":0.7401710899696038,"citation_network_contribution":0.0,"self_endowment_contribution":0.7401710899696038,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":138,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1642749,"name":"Ahmed S.I. Aly","orcid":null,"position":1,"is_corresponding":false},{"id":720226,"name":"Stefan H.I. Kappe","orcid":null,"position":2,"is_corresponding":false},{"id":447460,"name":"Ashley M. Vaughan","orcid":"0000-0001-5815-756X","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Malaria Parasite Pre-Erythrocytic Stage Infection: Gliding and Hiding","abstract":"In malaria, the red blood cell-infectious form of the Plasmodium parasite causes illness and the possible death of infected hosts. The initial infection in the liver caused by the mosquito-borne sporozoite parasite stage, however, causes little pathology and no symptoms. Nevertheless, pre-erythrocytic parasite stages are attracting passionate research efforts not least because they are the most promising targets for malaria vaccine development. Here, we review how the infectious sporozoite makes its way to the liver and subsequently develops within hepatocytes. We discuss the factors, both parasite and host, involved in the interactions that occur during this \"silent\" phase of infection.","is_dataset_classified":null,"base_score":4.9344739331306915,"endowment":4.9344739331306915,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"18779047","pmcid":"PMC2610487","openalex_id":"https://openalex.org/W2083522591","authors":[],"funders":[{"funder_name":"NIAID NIH HHS","grant_id":"R01 AI053709","title":null}],"total_grants":1,"fwci":7.1959,"citation_percentile":0.97039144,"influential_citations":0,"citation_trend":[{"year":2012,"count":12},{"year":2013,"count":8},{"year":2014,"count":7},{"year":2015,"count":10},{"year":2016,"count":8},{"year":2017,"count":10},{"year":2018,"count":12},{"year":2019,"count":9},{"year":2020,"count":8},{"year":2021,"count":7},{"year":2022,"count":9},{"year":2023,"count":8},{"year":2024,"count":3},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"bronze","license":"https://www.elsevier.com/open-access/userlicense/1.0/","oa_locations":[{"url":"http://www.cell.com/article/S1931312808002667/pdf","host_type":"journal"},{"url":"http://www.cell.com/article/S1931312808002667/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1931312808002667?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1931312808002667?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.chom.2008.08.010","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/18779047","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2610487","host_type":"repository"}],"fields_of_study":["Malaria Research and Control","Mosquito-borne diseases and control","Invertebrate Immune Response Mechanisms","Animals","Erythrocytes","Hepatocytes","Host-Parasite Interactions","Humans","Malaria","Merozoites","Plasmodium","Skin","Sporozoites"],"mesh_terms":["Animals","Erythrocytes","Host-Parasite Interactions","Humans","Malaria","Plasmodium","Skin","Hepatocytes","Sporozoites","Merozoites"],"keywords":["Parasite hosting","Malaria","Biology","Plasmodium (life cycle)","Virology","Immunology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T12:16:46.998302Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}