{"doi":"10.1016/j.cell.2010.05.011","title":"Cell Polarity in Eggs and Epithelia: Parallels and Diversity","abstract":null,"journal":"Cell","year":2010,"id":670071,"datarank":0.9294666191691782,"base_score":6.19644412779452,"endowment":6.19644412779452,"self_citation_contribution":0.9294666191691782,"citation_network_contribution":0.0,"self_endowment_contribution":0.9294666191691782,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":490,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":23415,"name":"Julie Ahringer","orcid":"0000-0002-7074-4051","position":1,"is_corresponding":false},{"id":398193,"name":"Daniel St Johnston","orcid":"0000-0001-5582-3301","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Cell Polarity in Eggs and Epithelia: Parallels and Diversity","abstract":"Cell polarity, the generation of cellular asymmetries, is necessary for diverse processes in animal cells, such as cell migration, asymmetric cell division, epithelial barrier function, and morphogenesis. Common mechanisms generate and transduce cell polarity in different cells, but cell type-specific processes are equally important. In this review, we highlight the similarities and differences between the polarity mechanisms in eggs and epithelia. We also highlight the prospects for future studies on how cortical polarity interfaces with other cellular processes, such as morphogenesis, exocytosis, and lipid signaling, and how defects in polarity contribute to tumor formation.","is_dataset_classified":null,"base_score":6.19644412779452,"endowment":6.19644412779452,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"20510924","pmcid":null,"openalex_id":"https://openalex.org/W1975338046","authors":[],"funders":[{"funder_name":"Wellcome Trust","grant_id":"080007","title":null},{"funder_name":"Wellcome Trust","grant_id":"unidentified","title":"unidentified"},{"funder_name":"Cancer Research UK","grant_id":"","title":null},{"funder_name":"Cancer Research UK","grant_id":"","title":null}],"total_grants":4,"fwci":19.16,"citation_percentile":0.99801567,"influential_citations":0,"citation_trend":[{"year":2012,"count":50},{"year":2013,"count":47},{"year":2014,"count":45},{"year":2015,"count":29},{"year":2016,"count":35},{"year":2017,"count":33},{"year":2018,"count":29},{"year":2019,"count":31},{"year":2020,"count":35},{"year":2021,"count":27},{"year":2022,"count":23},{"year":2023,"count":13},{"year":2024,"count":11},{"year":2025,"count":17},{"year":2026,"count":7}],"oa_status":"bronze","license":"Elsevier Non-Commercial","oa_locations":[{"url":"http://www.cell.com/article/S0092867410005477/pdf","host_type":"journal"},{"url":"http://www.cell.com/article/S0092867410005477/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0092867410005477?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0092867410005477?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.cell.2010.05.011","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/20510924","host_type":"repository"},{"url":"http://dx.doi.org/10.1016/j.cell.2010.05.011","host_type":""},{"url":"https://dx.doi.org/10.1016/j.cell.2010.05.011","host_type":""}],"fields_of_study":["Microtubule and mitosis dynamics","Reproductive Biology and Fertility","Genetics, Aging, and Longevity in Model Organisms","0301 basic medicine","0303 health sciences","03 medical and health sciences","Animals","Caenorhabditis elegans","Cell Line","Cell Polarity","Drosophila melanogaster","Embryo, Mammalian","Embryo, Nonmammalian","Epithelial Cells","Humans"],"mesh_terms":["Animals","Cell Line","Drosophila melanogaster","Embryo, Mammalian","Embryo, Nonmammalian","Epithelial Cells","Humans","Cell Polarity","Caenorhabditis elegans"],"keywords":["Cell polarity","Biology","Polarity (international relations)","Morphogenesis","Cell biology","Asymmetric cell division","Epithelial polarity","Cell","Exocytosis","Cell division","Cell type","Function (biology)","Genetics","Gene","Drosophila melanogaster","Embryo, Nonmammalian","Biochemistry, Genetics and Molecular Biology(all)","Animals","Humans","Epithelial Cells","Caenorhabditis elegans","Embryo, Mammalian","Cell Line"],"sdg_mappings":[],"linked_datasets":[{"doi":"10.6084/m9.figshare.12502751.v1","title":"Additional file 1 of Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.12502751","title":"Additional file 1 of Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-15T20:00:14.373136Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}