{"doi":"10.1016/j.cell.2007.09.029","title":"Retrovirus Silencing by an Epigenetic TRIM","abstract":null,"journal":"Cell","year":2007,"id":683304,"datarank":1.6503980761621173,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"self_citation_contribution":0.5101796072493234,"citation_network_contribution":1.1402184689127939,"self_endowment_contribution":0.5101796072493234,"citer_contribution":1.1402184689127939,"corpus_percentile":null,"corpus_rank":null,"citation_count":29,"citer_count":21,"citers_with_citation_signal":19,"citers_with_endowment":19,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":258725,"name":"Akitsu Hotta","orcid":"0000-0002-2619-7441","position":1,"is_corresponding":false},{"id":464946,"name":"Mojgan Rastegar","orcid":"0000-0003-3619-6116","position":2,"is_corresponding":false},{"id":570864,"name":"James Ellis","orcid":"0000-0002-4400-0091","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Retrovirus Silencing by an Epigenetic TRIM","abstract":"Embryonic cells silence transcription by retroviruses, but how do they recognize virus DNA? In this issue, Wolf and Goff (2007) report that a TRIM28 corepressor complex binds to the retrovirus primer binding site. Epigenetic silencing of retrovirus transcription is accomplished by \"writing\" a dimethyl mark on lysine 9 of histone H3 that is read by the heterochromatin protein HP1gamma.","is_dataset_classified":null,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17923079","pmcid":null,"openalex_id":"https://openalex.org/W2015192421","authors":[],"funders":[],"total_grants":0,"fwci":0.6917,"citation_percentile":0.7299954,"influential_citations":0,"citation_trend":[{"year":2012,"count":3},{"year":2013,"count":3},{"year":2014,"count":1},{"year":2015,"count":1},{"year":2016,"count":1},{"year":2017,"count":2},{"year":2018,"count":4},{"year":2021,"count":2},{"year":2022,"count":1},{"year":2023,"count":4},{"year":2024,"count":1}],"oa_status":"bronze","license":"http://www.elsevier.com/open-access/userlicense/1.0/","oa_locations":[{"url":"http://www.cell.com/article/S0092867407012172/pdf","host_type":"journal"},{"url":"http://www.cell.com/article/S0092867407012172/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0092867407012172?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0092867407012172?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.cell.2007.09.029","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/17923079","host_type":"repository"}],"fields_of_study":["Virus-based gene therapy research","CRISPR and Genetic Engineering","Viral Infectious Diseases and Gene Expression in Insects","Animals","Binding Sites","Chromosomal Proteins, Non-Histone","Embryonic Stem Cells","Epigenesis, Genetic","Gene Silencing","Histones","Humans","Nuclear Proteins","Regulatory Elements, Transcriptional","Repressor Proteins","Retroviridae","Transcription Factors","Transcription, Genetic","Tripartite Motif-Containing Protein 28"],"mesh_terms":["Tripartite Motif-Containing Protein 28","Animals","Binding Sites","Chromosomal Proteins, Non-Histone","Histones","Humans","Nuclear Proteins","Repressor Proteins","Retroviridae","Transcription Factors","Transcription, Genetic","Gene Silencing","Epigenesis, Genetic","Regulatory Elements, Transcriptional","Embryonic Stem Cells"],"keywords":["Biology","Retrovirus","Gene silencing","Epigenetics","Trim","Virology","Genetics","Computational biology","Virus","Gene"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T03:42:24.904044Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}