{"doi":"10.1016/j.cct.2025.107844","title":"A randomised controlled trial of a multidisciplinary TEAM-based approach to guide secondary cardiovascular risk reduction for patients with Peripheral Artery Disease (TEAM-PAD) study protocol","abstract":null,"journal":"Contemporary Clinical Trials","year":2025,"id":639121,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1660353,"name":"Sophie James","orcid":null,"position":1,"is_corresponding":false},{"id":1021241,"name":"Leonard Kritharides","orcid":"0000-0001-5818-8024","position":2,"is_corresponding":false},{"id":1011636,"name":"Janani Thillainadesan","orcid":"0000-0002-5287-7483","position":3,"is_corresponding":false},{"id":1660356,"name":"Samim Behdasht","orcid":null,"position":4,"is_corresponding":false},{"id":1660357,"name":"Shaundeep Sen","orcid":null,"position":5,"is_corresponding":false},{"id":1660358,"name":"Avinash Suryawanshi","orcid":null,"position":6,"is_corresponding":false},{"id":1660359,"name":"Huw Davie","orcid":null,"position":7,"is_corresponding":false},{"id":1660360,"name":"Amy Kitajima","orcid":null,"position":8,"is_corresponding":false},{"id":1660362,"name":"Sarah Joy Aitken","orcid":null,"position":9,"is_corresponding":false},{"id":1571826,"name":"Ritesh Chimoriya","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"A randomised controlled trial of a multidisciplinary TEAM-based approach to guide secondary cardiovascular risk reduction for patients with Peripheral Artery Disease (TEAM-PAD) study protocol","abstract":"BACKGROUND: Peripheral arterial disease (1) is a vascular condition associated with significant cardiovascular morbidity and mortality. Effective secondary prevention strategies are essential to improve cardiovascular outcomes in patients with PAD. The TEAM-PAD study aims to determine if a centralised virtual multidisciplinary team (MDT) model of care is effective in improving guideline-recommended secondary cardiovascular risk reduction for outpatients with PAD. METHODS: TEAM-PAD is a multicentre, randomised controlled trial involving patients with PAD. Participants will be randomised into two groups: the intervention group, who will receive care supported by cardiovascular risk reduction recommendations from a centralised MDT; and the control group, who will receive usual care by their vascular surgeon. The MDT will consist of the following clinicians: vascular surgeon, cardiologist, endocrinologist, nephrologist, geriatrician, drug health physician and clinical pharmacist. The primary outcome is the change in a composite measure of an individual's 10-year cardiovascular risk between baseline to 9-months follow-up. Secondary outcomes include control of modifiable cardiovascular risk factors and medication optimisation, cardiovascular and limb outcomes, PAD symptom control, quality of life outcomes, and health-service use outcomes. CONCLUSION: This article details the TEAM-PAD trial protocol, which will provide robust evidence on the benefits of an MDT-based approach to cardiovascular risk reduction in PAD patients. TEAM-PAD has the potential to inform clinical practice by demonstrating whether coordinated, personalised care recommendations can improve cardiovascular risk and potentially reduce cardiovascular events in this high-risk population. TRIAL REGISTRATION: This study has been registered at the Australia New Zealand Clinical Trial Registry (Registration number: ACTRN12623000995673).","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39952552","pmcid":null,"openalex_id":"https://openalex.org/W4407405898","authors":[],"funders":[],"total_grants":0,"fwci":3.2344,"citation_percentile":0.90143959,"influential_citations":0,"citation_trend":[{"year":2025,"count":3}],"oa_status":"hybrid","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1016/j.cct.2025.107844","host_type":"journal"},{"url":"https://doi.org/10.1016/j.cct.2025.107844","host_type":"HYBRID"},{"url":"https://doi.org/10.1016/j.cct.2025.107844","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1551714425000382?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1551714425000382?httpAccept=text/plain","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39952552","host_type":"repository"}],"fields_of_study":["Peripheral Artery Disease Management","Cardiac, Anesthesia and Surgical Outcomes","Antiplatelet Therapy and Cardiovascular Diseases","Medicine","Humans","Peripheral Arterial Disease","Patient Care Team","Secondary Prevention","Randomized Controlled Trials as Topic","Cardiovascular Diseases","Multicenter Studies as Topic","Quality of Life","Risk Reduction Behavior","Heart Disease Risk Factors"],"mesh_terms":["Heart Disease Risk Factors","Aged","Cardiovascular Diseases","Female","Humans","Male","Patient Care Team","Quality of Life","Multicenter Studies as Topic","Randomized Controlled Trials as Topic","Risk Reduction Behavior","Secondary Prevention","Peripheral Arterial Disease"],"keywords":["Medicine","Arterial disease","Protocol (science)","Multidisciplinary approach","Multidisciplinary team","Secondary prevention","Physical therapy","Disease","Randomized controlled trial","Physical medicine and rehabilitation","Vascular disease","Surgery","Alternative medicine","Internal medicine","Nursing","Pathology","Cardiovascular","Clinical trial","MDT","Peripheral arterial disease","Vascular surgery"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T22:33:35.588436Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}