{"doi":"10.1016/j.cct.2022.107007","title":"A randomized controlled trial of a shared decision making intervention for diabetes prevention for women with a history of gestational diabetes mellitus: The Gestational diabetes Risk Attenuation for New Diabetes (GRAND study)","abstract":"BACKGROUND: Gestational diabetes mellitus (GDM) is a risk factor for the development of type 2 diabetes. Metformin and lifestyle change through a Diabetes Prevention Program (DPP) are equally effective in preventing diabetes in patients with a GDM history, so women can choose a strategy based on their preferences. This study aims to test whether shared decision making (SDM) can help women with a history of GDM increase adoption of evidence-based strategies and lose weight to lower their risk of incident diabetes in real-world settings. METHODS: This pragmatic randomized controlled trial (RCT) will test the effectiveness of SDM for diabetes prevention among 310 overweight/obese women with a history of GDM and prediabetes from two large health care systems (n = 155 from UCLA Health and n = 155 from Intermountain Healthcare). The primary outcome is the proportion of participants who lose ≥5% body weight at 12 months. Secondary outcomes include uptake of DPP and/or metformin and other patient-reported outcomes such as patient activation and health-related quality of life. Rates of GDM in a subsequent pregnancy will be an exploratory outcome. A descriptive analysis of costs related to SDM implementation will also be conducted. CONCLUSION: This is the first RCT to examine the effectiveness of SDM on weight loss, lifestyle change and/or metformin use, and other patient-reported outcomes in participants with a GDM history at risk of developing diabetes. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03766256. Registered on 6 December 2018.","journal":"Contemporary Clinical Trials","year":2022,"id":282897,"datarank":0.3865225833133199,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.07460635206134444,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.07460635206134444,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":5,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9553,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT03766256"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":925887,"name":"Amanda Vu","orcid":"0000-0001-8362-2865","position":1,"is_corresponding":false},{"id":926354,"name":"Felicia Cheng","orcid":null,"position":2,"is_corresponding":false},{"id":926355,"name":"Janet Chon","orcid":null,"position":3,"is_corresponding":false},{"id":542216,"name":"Norman Turk","orcid":null,"position":4,"is_corresponding":false},{"id":959801,"name":"Ashley Krueger","orcid":null,"position":5,"is_corresponding":false},{"id":959802,"name":"Jacob Krong","orcid":null,"position":6,"is_corresponding":false},{"id":959803,"name":"Richard Maranon","orcid":null,"position":7,"is_corresponding":false},{"id":959804,"name":"Sandra Liu","orcid":null,"position":8,"is_corresponding":false},{"id":678709,"name":"Christina S. Han","orcid":"0000-0003-1627-3057","position":9,"is_corresponding":false},{"id":308459,"name":"Keith C. Norris","orcid":"0000-0003-3071-0700","position":10,"is_corresponding":false},{"id":409457,"name":"Carol M. Mangione","orcid":"0000-0002-9475-2275","position":11,"is_corresponding":false},{"id":959298,"name":"Jessica Page","orcid":"0000-0001-7686-8015","position":12,"is_corresponding":false},{"id":959299,"name":"Samuel Thomas","orcid":"0000-0001-9264-2358","position":13,"is_corresponding":false},{"id":453462,"name":"O. Kenrik Duru","orcid":"0000-0001-8825-9460","position":14,"is_corresponding":false},{"id":443924,"name":"Tannaz Moin","orcid":"0000-0002-5035-6641","position":15,"is_corresponding":false},{"id":925888,"name":"Ruth Madievsky","orcid":"0000-0001-6229-3070","position":0,"is_corresponding":true}],"reference_count":47,"raw_metadata":null,"created_at":"2026-07-19T00:29:23.777809Z","pmid":"36384219","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}