{"doi":"10.1016/j.canlet.2020.08.021","title":"Non-coding RNA in thyroid cancer - Functions and mechanisms","abstract":null,"journal":"Cancer Letters","year":2021,"id":665194,"datarank":0.6554171778700533,"base_score":4.3694478524670215,"endowment":4.3694478524670215,"self_citation_contribution":0.6554171778700533,"citation_network_contribution":0.0,"self_endowment_contribution":0.6554171778700533,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":78,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1276686,"name":"Mengdi Zhang","orcid":"0000-0003-4423-4899","position":1,"is_corresponding":false},{"id":188572,"name":"Long Zhang","orcid":null,"position":2,"is_corresponding":false},{"id":1736997,"name":"Jianlin Lou","orcid":null,"position":3,"is_corresponding":false},{"id":188573,"name":"Fangfang Zhou","orcid":null,"position":4,"is_corresponding":false},{"id":1736998,"name":"Meiyu Fang","orcid":null,"position":5,"is_corresponding":false},{"id":656601,"name":"Jun Cao","orcid":"0000-0002-5591-2299","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Non-coding RNA in thyroid cancer - Functions and mechanisms","abstract":"Thyroid cancer is the most common endocrine malignant tumor, and its incidence has increased significantly in the past few years. A growing number of noncoding RNAs (ncRNAs) have shown abnormal expression patterns in human thyroid cancer in recent studies. Depending on size, ncRNAs are usually subdivided into two categories: short ncRNAs and long ncRNAs (longer than 200 nucleotides). Short ncRNAs include microRNAs (miRNAs), PIWI-interacting RNAs, small nucleolar RNAs, and endogenous small interfering RNAs, which have been extensively studied due to their roles in developmental and tumor biology. Compared to that of short ncRNAs, the involvement of lncRNAs in human cancers, especially in thyroid cancer, is not as well studied. Here, we reviewed the roles and clinical significance of miRNAs, lncRNAs, and circular RNA in thyroid development, tumorigenesis, and metastasis to offer a new approach to thyroid cancer treatment.","is_dataset_classified":null,"base_score":4.3694478524670215,"endowment":4.3694478524670215,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"32949678","pmcid":null,"openalex_id":"https://openalex.org/W3087674383","authors":[],"funders":[{"funder_name":"Natural Science Foundation of Jiangsu Province","grant_id":"","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"","title":null},{"funder_name":"Medical Science and Technology Project of Zhejiang Province","grant_id":"","title":null},{"funder_name":"Ministry of Science and Technology of the People's Republic of China","grant_id":"","title":null},{"funder_name":"Natural Science Foundation of Zhejiang Province","grant_id":"","title":null}],"total_grants":5,"fwci":3.395,"citation_percentile":0.94929475,"influential_citations":0,"citation_trend":[{"year":2021,"count":11},{"year":2022,"count":20},{"year":2023,"count":17},{"year":2024,"count":15},{"year":2025,"count":11},{"year":2026,"count":4}],"oa_status":"hybrid","license":"cc-by-nc-nd","oa_locations":[{"url":"https://doi.org/10.1016/j.canlet.2020.08.021","host_type":"journal"},{"url":"https://doi.org/10.1016/j.canlet.2020.08.021","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/32949678","host_type":"repository"}],"fields_of_study":["Cancer-related molecular mechanisms research","Circular RNAs in diseases","MicroRNA in disease regulation","Animals","Gene Expression Regulation, Neoplastic","Humans","RNA, Untranslated","Thyroid Neoplasms"],"mesh_terms":["Animals","Humans","Thyroid Neoplasms","Gene Expression Regulation, Neoplastic","RNA, Untranslated"],"keywords":["Piwi-interacting RNA","microRNA","Carcinogenesis","Thyroid cancer","RNA","Biology","Small nucleolar RNA","Thyroid","Cancer","Long non-coding RNA","Non-coding RNA","Metastasis","Computational biology","Cancer research","Bioinformatics","Genetics","RNA interference","Gene","Thyroid Cancer Treatment","Mechanism Of Action Of Noncoding Rna"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-13T07:53:15.798714Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}