{"doi":"10.1016/j.brainres.2018.01.033","title":"Intrinsic optical imaging study on cortical responses to electrical stimulation in ventral posterior medial nucleus of thalamus","abstract":null,"journal":"Brain Research","year":2018,"id":593306,"datarank":0.4861422038827765,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.21737828349856825,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.21737828349856825,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":3,"citers_with_citation_signal":3,"citers_with_endowment":3,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":345240,"name":"Shaomin Zhang","orcid":"0000-0001-6311-5946","position":1,"is_corresponding":false},{"id":1518511,"name":"Chaonan Yu","orcid":null,"position":2,"is_corresponding":false},{"id":1518512,"name":"Xiaoxiang Zheng","orcid":null,"position":3,"is_corresponding":false},{"id":1518513,"name":"Kedi Xu","orcid":null,"position":4,"is_corresponding":false},{"id":883319,"name":"Jiacheng Zhang","orcid":"0000-0002-8671-5888","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Intrinsic optical imaging study on cortical responses to electrical stimulation in ventral posterior medial nucleus of thalamus","abstract":"Intracortical electrical micro-stimulation has been applied widely for the attempts on reconstruction of sensory functions. More recently, thalamic electrical stimulation has been proposed as a promising target for somatosensory stimulation. However, the cortical activations and mechanisms evoked by VPM stimulation remained unclear. In this report, the cortical neural responses to electrical stimulations were recorded by optical imaging of intrinsic signals. The impact of stimulation parameters was characterized to illustrate how the VPM stimulation alter cortical activities. Significant increases were found in cortical responses with increased stimulation amplitude or pulse width. However, frequency modulation exhibited significant inhibition with higher frequency stimulation. Our results suggest that optical imaging of intrinsic signals is sensitive and reliable to deep brain stimulations. These results may not only help to understand the modulation effects through thalamocortical pathway, but also show the possibility to use VPM stimulation to evoke frequency-tuned tactile sensations in rats.","is_dataset_classified":null,"base_score":1.791759469228055,"endowment":1.791759469228055,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"29408501","pmcid":null,"openalex_id":"https://openalex.org/W2791492122","authors":[],"funders":[{"funder_name":"National Key Research and Development Program of China","grant_id":"grant number 2017YFC1308501","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"31627802","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"61233015","title":null},{"funder_name":"Public Projects of Zhejiang Province","grant_id":"2016C33059","title":null},{"funder_name":"Fundamental Research Funds for the Central Universities","grant_id":"2016XZZX001-10","title":null}],"total_grants":5,"fwci":0.4363,"citation_percentile":0.57147673,"influential_citations":0,"citation_trend":[{"year":2019,"count":1},{"year":2020,"count":2},{"year":2021,"count":1},{"year":2022,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0006899318300477?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0006899318300477?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.brainres.2018.01.033","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/29408501","host_type":"repository"}],"fields_of_study":["Neural dynamics and brain function","Neuroscience and Neural Engineering","Photoreceptor and optogenetics research","Animals","Behavior, Animal","Deep Brain Stimulation","Electric Stimulation","Neurons","Rats, Sprague-Dawley","Reaction Time","Sensation","Somatosensory Cortex","Thalamus","Ventral Thalamic Nuclei"],"mesh_terms":["Animals","Behavior, Animal","Electric Stimulation","Neurons","Reaction Time","Sensation","Somatosensory Cortex","Thalamus","Rats, Sprague-Dawley","Ventral Thalamic Nuclei","Deep Brain Stimulation"],"keywords":["Stimulation","Neuroscience","Thalamus","Somatosensory system","Sensory system","Deep brain stimulation","Sensory stimulation therapy","Brain stimulation","Electrical brain stimulation","Psychology","Thalamic stimulator","Medicine","Internal medicine","Somatosensory cortex","Intrinsic Optical Imaging","Micro-electrical Stimulation","Ventral Posterior Medial Nucleus Of Thalamus"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-26T20:08:07.092224Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}