{"doi":"10.1016/j.brainres.2015.08.013","title":"Lineage, fate, and fate potential of NG2-glia","abstract":null,"journal":"Brain Research","year":2016,"id":609899,"datarank":0.7206031567099886,"base_score":4.804021044733257,"endowment":4.804021044733257,"self_citation_contribution":0.7206031567099886,"citation_network_contribution":0.0,"self_endowment_contribution":0.7206031567099886,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":121,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1567808,"name":"Linda Boshans","orcid":null,"position":1,"is_corresponding":false},{"id":1567809,"name":"Christopher M. Goncalves","orcid":null,"position":2,"is_corresponding":false},{"id":269790,"name":"Jill Wegrzyn","orcid":"0000-0001-5923-0888","position":3,"is_corresponding":false},{"id":402376,"name":"Kiran D. Patel","orcid":"0000-0003-3769-482X","position":4,"is_corresponding":false},{"id":448958,"name":"Akiko Nishiyama","orcid":"0000-0001-7252-0812","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Lineage, fate, and fate potential of NG2-glia","abstract":"NG2 cells represent a fourth major glial cell population in the mammalian central nervous system (CNS). They arise from discrete germinal zones in mid-gestation embryos and expand to occupy the entire CNS parenchyma. Genetic fate mapping studies have shown that oligodendrocytes and a subpopulation of ventral protoplasmic astrocytes arise from NG2 cells. This review describes recent findings on the fate and fate potential of NG2 cells under physiological and pathological conditions. We discuss age-dependent changes in the fate and fate potential of NG2 cells and possible mechanisms that could be involved in restricting their oligodendrocyte differentiation or fate plasticity. This article is part of a Special Issue entitled SI:NG2-glia(Invited only).","is_dataset_classified":null,"base_score":4.804021044733257,"endowment":4.804021044733257,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26301825","pmcid":"PMC4761528","openalex_id":"https://openalex.org/W1140975977","authors":[],"funders":[{"funder_name":"NIH","grant_id":"R01 NS073425","title":null},{"funder_name":"NIH","grant_id":"R01 NS074870","title":null},{"funder_name":"National Multiple Sclerosis Society","grant_id":"RG4579","title":null},{"funder_name":"National Institutes of Health","grant_id":"4R01NS074870-05","title":"Heterogeneity of NG2 Glial Cells"},{"funder_name":"National Institutes of Health","grant_id":"5R01NS073425-02","title":"Inflammation and NG2 Cell Differentiation"}],"total_grants":5,"fwci":5.0271,"citation_percentile":0.9595186,"influential_citations":0,"citation_trend":[{"year":2016,"count":5},{"year":2017,"count":12},{"year":2018,"count":14},{"year":2019,"count":11},{"year":2020,"count":17},{"year":2021,"count":25},{"year":2022,"count":8},{"year":2023,"count":13},{"year":2024,"count":6},{"year":2025,"count":5},{"year":2026,"count":5}],"oa_status":"green","license":"Elsevier TDM","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4761528","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4761528","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S0006899315006307?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0006899315006307?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.brainres.2015.08.013","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/26301825","host_type":"repository"},{"url":"https://europepmc.org/articles/pmc4761528?pdf=render","host_type":""},{"url":"https://dx.doi.org/10.1016/j.brainres.2015.08.013","host_type":""}],"fields_of_study":["Neurogenesis and neuroplasticity mechanisms","MicroRNA in disease regulation","RNA Research and Splicing","0301 basic medicine","0303 health sciences","03 medical and health sciences"],"mesh_terms":["Chondroitin Sulfate Proteoglycan 4","Animals","Antigens","Central Nervous System","Humans","Neuroglia","Proteoglycans","Stem Cells","Cell Lineage"],"keywords":["Fate mapping","Cell fate determination","Biology","Oligodendrocyte","Neuroscience","Parenchyma","Gliogenesis","Neuroglia","Population","Cell biology","Central nervous system","Neural stem cell","Stem cell","Myelin","Genetics","Progenitor cell","Lineage","Cell Fate","Ng2","Polydendrocyte","Stem Cells","Animals","Humans","Cell Lineage","Proteoglycans","Antigens","Chondroitin Sulfate Proteoglycan 4"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-31T17:15:12.386986Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}