{"doi":"10.1016/j.braindev.2021.06.005","title":"Virus reactivation after immunotherapy of anti-NMDAR encephalitis secondary to herpes simplex encephalitis: A case report","abstract":null,"journal":"Brain and Development","year":2021,"id":640665,"datarank":0.24141568686511508,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1665168,"name":"Zhengxiong Yao","orcid":null,"position":1,"is_corresponding":false},{"id":1439884,"name":"Li Jiang","orcid":"0000-0001-8504-7497","position":2,"is_corresponding":false},{"id":1665169,"name":"Chengbing Tan","orcid":null,"position":3,"is_corresponding":false},{"id":397264,"name":"Yan Jiang","orcid":"0000-0002-1945-4200","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Virus reactivation after immunotherapy of anti-NMDAR encephalitis secondary to herpes simplex encephalitis: A case report","abstract":"Herpes simplex encephalitis is the most common cause of sporadic fatal encephalitis. More than half of patients with herpes simplex encephalitis will die and the vast majority of survivors have severe neurologic sequelae without effective antiviral therapy. Some people experience relapses such as secondary anti-N-methyl-d-aspartate receptor encephalitis despite appropriate antiviral treatment. It is rare that virus reactivation after immunotherapy of anti-N-methyl-d-aspartate receptor encephalitis after herpes simplex encephalitis. In the present study, we retrospectively review one patient who showed this rare situation.","is_dataset_classified":null,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34243963","pmcid":null,"openalex_id":"https://openalex.org/W3180819330","authors":[],"funders":[],"total_grants":0,"fwci":0.4151,"citation_percentile":0.6373535,"influential_citations":0,"citation_trend":[{"year":2022,"count":3},{"year":2023,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0387760421001236?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0387760421001236?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.braindev.2021.06.005","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34243963","host_type":"repository"}],"fields_of_study":["Autoimmune Neurological Disorders and Treatments","Infectious Encephalopathies and Encephalitis","Herpesvirus Infections and Treatments"],"mesh_terms":["Child","Humans","Immunologic Factors","Encephalitis, Herpes Simplex","Anti-N-Methyl-D-Aspartate Receptor Encephalitis"],"keywords":["Encephalitis","Herpes simplex virus","Medicine","Immunotherapy","Autoimmune encephalitis","Virology","Immunology","Virus","Immune system","Pediatric","Anti-n-methyl-d-aspartate Receptor Encephalitis","Virus Reactivation","Herpes Simplex Encephalitis"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T13:12:45.907983Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}