{"doi":"10.1016/j.bmcl.2011.01.134","title":"Discovery of histone deacetylase 8 selective inhibitors","abstract":null,"journal":"Bioorganic & Medicinal Chemistry Letters","year":2011,"id":635435,"datarank":0.6782682865573562,"base_score":4.5217885770490405,"endowment":4.5217885770490405,"self_citation_contribution":0.6782682865573562,"citation_network_contribution":0.0,"self_endowment_contribution":0.6782682865573562,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":91,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":294887,"name":"Tuoping Luo","orcid":"0000-0003-2156-3198","position":1,"is_corresponding":false},{"id":348412,"name":"Edward F. 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These compounds were assayed without further purification. HDAC8-selective inhibitors were discovered from this novel collection of compounds.","is_dataset_classified":null,"base_score":4.5217885770490405,"endowment":4.5217885770490405,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21334896","pmcid":"PMC3403710","openalex_id":"https://openalex.org/W1989811175","authors":[],"funders":[{"funder_name":"NCI NIH HHS","grant_id":"K08 CA128972","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM038627","title":null},{"funder_name":"PHS HHS","grant_id":"NIGMS 38627","title":null},{"funder_name":"Howard Hughes Medical Institute","grant_id":"","title":null},{"funder_name":"Howard Hughes Medical Institute","grant_id":"","title":null}],"total_grants":5,"fwci":3.7711,"citation_percentile":0.94313517,"influential_citations":0,"citation_trend":[{"year":2012,"count":15},{"year":2013,"count":7},{"year":2014,"count":5},{"year":2015,"count":7},{"year":2016,"count":13},{"year":2017,"count":4},{"year":2018,"count":6},{"year":2019,"count":6},{"year":2020,"count":4},{"year":2021,"count":3},{"year":2022,"count":5},{"year":2023,"count":4},{"year":2024,"count":5},{"year":2025,"count":3}],"oa_status":"green","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://doi.org/10.7270/q2zc835m","host_type":"repository"},{"url":"https://doi.org/10.7270/q2zc835m","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S0960894X11001685?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0960894X11001685?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.bmcl.2011.01.134","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21334896","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3403710","host_type":"repository"}],"fields_of_study":["Histone Deacetylase Inhibitors Research","Protein Degradation and Inhibitors","Peptidase Inhibition and Analysis","Biological Assay","Enzyme Activation","Histone Deacetylase Inhibitors","Histone Deacetylases","Humans","Inhibitory Concentration 50","Molecular Structure","Repressor Proteins"],"mesh_terms":["Biological Assay","Enzyme Activation","Histone Deacetylases","Humans","Repressor Proteins","Molecular Structure","Inhibitory Concentration 50","Histone Deacetylase Inhibitors"],"keywords":["Chemistry","Histone deacetylase","HDAC8","Hydrazide","Linker","Hydroxamic acid","Histone deacetylase inhibitor","Combinatorial chemistry","High-throughput screening","Aldehyde","Biochemistry","Histone","Stereochemistry","Organic chemistry","Catalysis","Gene"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T15:06:36.701971Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}