{"doi":"10.1016/j.bbih.2024.100861","title":"Stressful life events across the lifespan and inflammation: An integrative data analysis","abstract":"= 66.1) completed retrospective surveys of stressful life events and indicated what year(s) each event occurred and had blood drawn ∼4.5 years later. Stressful events were summed across the participants' lifespans (age 0 to current age) and within childhood (0-17 years), young adulthood (18-39), midlife (40-59), and late adulthood (60+). In main effects models, more cumulative stressors (γ = .05, SE = .02, p = .012) and stressors in young adulthood (γ = .06, SE = .03, p = .037) were associated with higher levels of CRP. In models with all life stages together among adults age 65+ (n = 4,972), experiencing more stressors in midlife significantly predicted higher levels of CRP (γ = .08, SE = .04, p = .038). Our findings replicate prior evidence of an association between cumulative stressors and inflammation and extend this work by identifying stressors in young adulthood and midlife as potentially unique sensitive periods that predict higher levels of later-life inflammation.","journal":"Brain Behavior & Immunity - Health","year":2024,"id":450675,"datarank":0.3498438347286963,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.10842814786358121,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.10842814786358121,"corpus_percentile":49.663495010443256,"corpus_rank":6508,"citation_count":4,"citer_count":3,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.7069,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1040720,"name":"Roma Dhingra","orcid":"0000-0002-9772-7403","position":1,"is_corresponding":false},{"id":554094,"name":"Rebecca G. Reed","orcid":"0000-0003-0794-594X","position":2,"is_corresponding":false},{"id":1271176,"name":"Abby R. Hillmann","orcid":"0000-0001-6038-3558","position":0,"is_corresponding":true}],"reference_count":63,"raw_metadata":null,"created_at":"2026-07-19T02:02:28.969209Z","pmid":"39381368","pmcid":"PMC11459650","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}