{"doi":"10.1016/j.annepidem.2021.08.021","title":"Projecting the age-distribution of men who have sex with men receiving HIV treatment in the United States","abstract":"BACKGROUND: The age-distribution of men who have sex with men (MSM) continues to change in the 'Treat-All' era as effective test-and-treat programs target key-populations. However, the nature of these changes and potential racial heterogeneities remain uncertain. METHODS: The PEARL model is an agent-based simulation of MSM in HIV care in the US, calibrated to data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). RESULTS: PEARL projects a gradual decrease in median age of MSM at ART initiation from 36 to 31 years during 2010-2030, accompanied by changes in mortality among Black, White, and Hispanic MSM on ART by -8.4%, 42.4% and -19.6%. The median age of all MSM on ART is projected to increase from 45 to 47 years from 2010-2030, with the proportion of ART-users age ≥60y increasing from 6.7% to 28.0%. Almost half (49.7%) of White MSM ART-users are projected to age ≥60y by 2030, compared to 19.5% of Black and 17.2% of Hispanic MSM. CONCLUSIONS: The overall age of US MSM in HIV care is expected to increase over the next decade, and differentially by race/ethnicity. As this population age, HIV programs should expand care for age-related causes of morbidity and mortality.","journal":"Annals of Epidemiology","year":2021,"id":190363,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":14,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7025,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":449211,"name":"Cameron Stewart","orcid":"0000-0002-9982-5808","position":1,"is_corresponding":false},{"id":449207,"name":"Elizabeth Humes","orcid":"0000-0003-3432-7688","position":2,"is_corresponding":false},{"id":450227,"name":"Lucas Gerace","orcid":null,"position":3,"is_corresponding":false},{"id":437633,"name":"Jinbing Zhang","orcid":"0000-0001-8606-1864","position":4,"is_corresponding":false},{"id":14779,"name":"Michael J. Silverberg","orcid":"0000-0001-9322-1395","position":5,"is_corresponding":false},{"id":240247,"name":"Michael A. Horberg","orcid":"0000-0002-6971-7646","position":6,"is_corresponding":false},{"id":240239,"name":"Peter F. Rebeiro","orcid":"0000-0003-1951-9104","position":7,"is_corresponding":false},{"id":273590,"name":"Emily P. Hyle","orcid":"0000-0001-8721-106X","position":8,"is_corresponding":false},{"id":240252,"name":"Viviane D. Lima","orcid":"0000-0003-4943-091X","position":9,"is_corresponding":false},{"id":240250,"name":"Cherise Wong","orcid":"0000-0003-2071-883X","position":10,"is_corresponding":false},{"id":240244,"name":"M. John Gill","orcid":"0000-0002-8546-8790","position":11,"is_corresponding":false},{"id":311291,"name":"Kelly A. Gebo","orcid":"0000-0003-4010-398X","position":12,"is_corresponding":false},{"id":240242,"name":"Richard D. Moore","orcid":"0000-0001-8250-5069","position":13,"is_corresponding":false},{"id":340159,"name":"Mari M. Kitahata","orcid":"0000-0002-5410-7175","position":14,"is_corresponding":false},{"id":240243,"name":"Keri N. Althoff","orcid":"0000-0002-5068-6595","position":15,"is_corresponding":false},{"id":413290,"name":"Parastu Kasaie","orcid":"0000-0002-3744-9501","position":0,"is_corresponding":true}],"reference_count":23,"raw_metadata":null,"created_at":"2026-07-18T23:49:26.966524Z","pmid":"34627998","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}