{"doi":"10.1016/j.ajog.2004.11.035","title":"Chorioamnionitis increases neonatal morbidity in pregnancies complicated by preterm premature rupture of membranes","abstract":null,"journal":"American Journal of Obstetrics and Gynecology","year":2005,"id":651037,"datarank":0.7878410142069946,"base_score":5.25227342804663,"endowment":5.25227342804663,"self_citation_contribution":0.7878410142069946,"citation_network_contribution":0.0,"self_endowment_contribution":0.7878410142069946,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":190,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":4,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1697786,"name":"Joelle M. Lieman","orcid":null,"position":1,"is_corresponding":false},{"id":1697787,"name":"Cynthia G. Brumfield","orcid":null,"position":2,"is_corresponding":false},{"id":1697788,"name":"Waldemar Carlo","orcid":null,"position":3,"is_corresponding":false},{"id":1153646,"name":"Patrick S. Ramsey","orcid":"0000-0002-2613-9364","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Chorioamnionitis increases neonatal morbidity in pregnancies complicated by preterm premature rupture of membranes","abstract":"<h4>Objective</h4>To compare morbidities of neonates born to women who developed chorioamnionitis after premature preterm rupture of membranes versus those who did not.<h4>Study design</h4>We reviewed outcomes in singleton pregnancies with confirmed premature preterm rupture of membranes at 24 weeks or beyond that resulted in delivery less than 37 weeks. Management of premature preterm rupture of membranes included the use of antibiotics, betamethasone if less than 32 weeks, and expectant management with induction at 34 weeks or greater. Composite neonatal major and minor morbidity rates were compared between pregnancies complicated by chorioamnionitis and those that were not.<h4>Results</h4>From August 1998 to August 2000, 430 cases of premature preterm rupture of membranes were identified among 6003 deliveries (7.2%). Thirteen percent of women (56/430) with premature preterm rupture of membranes developed chorioamnionitis. The incidence of chorioamnionitis increased significantly with decreasing gestational age. The composite neonatal major morbidity rate was significantly higher in neonates whose mothers developed chorioamnionitis (55%) versus those who did not (18%, P < .0001). In a multiple logistic regression model, chorioamnionitis ( P < .0001), infant gender ( P = .007), latency ( P = .03), and gestational age at delivery ( P < .0001) were significantly associated with composite neonatal morbidity.<h4>Conclusion</h4>Neonatal morbidities are significantly higher among pregnancies with premature preterm rupture of membranes complicated by chorioamnionitis when compared with pregnancies that were not.","is_dataset_classified":null,"base_score":5.25227342804663,"endowment":5.25227342804663,"datacite_reuse_total":4,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15846196","pmcid":null,"openalex_id":"https://openalex.org/W2019571417","authors":[],"funders":[{"funder_name":"NICHD NIH HHS","grant_id":"1 K12 HD01402","title":null}],"total_grants":1,"fwci":6.4958,"citation_percentile":0.97189333,"influential_citations":8,"citation_trend":[{"year":2012,"count":14},{"year":2013,"count":6},{"year":2014,"count":3},{"year":2015,"count":11},{"year":2016,"count":7},{"year":2017,"count":10},{"year":2018,"count":8},{"year":2019,"count":12},{"year":2020,"count":12},{"year":2021,"count":11},{"year":2022,"count":9},{"year":2023,"count":7},{"year":2024,"count":7},{"year":2025,"count":8},{"year":2026,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0002937804019933?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0002937804019933?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.ajog.2004.11.035","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15846196","host_type":"repository"}],"fields_of_study":["Preterm Birth and Chorioamnionitis","Reproductive tract infections research","Reproductive System and Pregnancy","Medicine"],"mesh_terms":["Adolescent","Adult","Apgar Score","Chorioamnionitis","Female","Premature Rupture of Fetal Membranes","Fetal Membranes, Premature Rupture","Follow-Up Studies","Gestational Age","Humans","Infant, Newborn","Infant, Newborn, Diseases","Obstetric Labor, Premature","Pregnancy","Pregnancy Outcome","Probability","Reference Values","Retrospective Studies","Severity of Illness Index","Incidence","Multivariate Analysis","Logistic Models","Case-Control Studies","Risk Assessment"],"keywords":["Chorioamnionitis","Medicine","Premature rupture of membranes","Gestational age","Obstetrics","Incidence (geometry)","Betamethasone","Rupture of membranes","Pregnancy","Premature birth","Gestation","Pediatrics","Internal medicine"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.19582357.v1","title":"Additional file 2 of Suspected clinical chorioamnionitis with peak intrapartum temperature &lt;380C: the prevalence of confirmed chorioamnionitis and short term neonatal outcome","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.19582357","title":"Additional file 2 of Suspected clinical chorioamnionitis with peak intrapartum temperature &lt;380C: the prevalence of confirmed chorioamnionitis and short term neonatal outcome","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26622025.v1","title":"Additional file 1 of Predictors of extubation failure in newborns: a systematic review and meta-analysis","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26622025","title":"Additional file 1 of Predictors of extubation failure in newborns: a systematic review and meta-analysis","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T06:32:16.952588Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}