{"doi":"10.1016/j.afjem.2020.09.007","title":"A retrospective comparison of the burden of organophosphate poisoning to an Intensive Care Unit in Soweto over two separate periods","abstract":null,"journal":"African Journal of Emergency Medicine","year":2021,"id":615520,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1586540,"name":"Imtiaz A. Bahemia","orcid":null,"position":1,"is_corresponding":false},{"id":1586541,"name":"Lara Toerien","orcid":null,"position":2,"is_corresponding":false},{"id":1586542,"name":"Karyll M. San Pedro","orcid":null,"position":3,"is_corresponding":false},{"id":1586543,"name":"Ayesha B. Khan","orcid":null,"position":4,"is_corresponding":false},{"id":1586539,"name":"Shahed Omar","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"A retrospective comparison of the burden of organophosphate poisoning to an Intensive Care Unit in Soweto over two separate periods","abstract":"INTRODUCTION: Organophosphate poisoning (OPP) is a major health-care burden in South Africa. Recently, we have observed that patients admitted to our Intensive Care Unit (ICU) with OPP have followed a more complicated course in comparison to previous years. OBJECTIVES: To describe the differences in the clinical course and costs of patients with OPP between two time periods, namely 2012 and 2017. METHODS: Retrospective comparison of patients admitted to the Intensive Care Unit (ICU) of Chris Hani Baragwanath Academic Hospital between January 2012 to December 2012 and January 2017 to December 2017. RESULTS: Forty-one patients were found in the database. Patients from our 2017 cohort showed a significantly longer total median (IQR) length of stay 8 (4-17) days vs. 2 (2-3) days, p = 0.000, duration of antidote therapy 5 (3-10) days vs. 2 (2-3) days, p = 0.004 and duration of ventilation 4 (2-11) days vs 1 (1-2) day, p = 0.003. Patients presenting in 2017 were more likely to be admitted to ICU, odds ratio 5.6 (CI 1.2-26). There was a 31- fold increase in ICU costs between 2012 and 2017. CONCLUSION: Based on our experience, the clinical course of OPP requiring ICU admission has evolved into a condition with a longer length of stay, duration of antidote therapy, ventilatory support, increased risk of complications and additional costs.","is_dataset_classified":null,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"33680732","pmcid":"PMC7910160","openalex_id":"https://openalex.org/W3092321312","authors":[],"funders":[],"total_grants":0,"fwci":1.2961,"citation_percentile":0.83550407,"influential_citations":0,"citation_trend":[{"year":2021,"count":2},{"year":2022,"count":1},{"year":2023,"count":3},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"https://www.sciencedirect.com/science/article/pii/S2211419X2030104X/pdf","host_type":"journal"},{"url":"https://www.sciencedirect.com/science/article/pii/S2211419X2030104X/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2211419X2030104X?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2211419X2030104X?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.afjem.2020.09.007","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/33680732","host_type":"repository"},{"url":"https://doaj.org/article/3521c19ad32344dd89aa515e97dba7d7","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7910160","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC7910160","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC7910160?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Pesticide Exposure and Toxicity","Poisoning and overdose treatments","Pesticide and Herbicide Environmental Studies"],"mesh_terms":[],"keywords":["Medicine","Intensive care unit","Retrospective cohort study","Antidote","Emergency medicine","Mechanical ventilation","Odds ratio","Cohort","Intensive care","Pediatrics","Intensive care medicine","Anesthesia","Internal medicine","Toxicity","Poisoning","Africa","Organophosphorus","toxicology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T20:14:25.279997Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}