{"doi":"10.1016/j.adro.2020.09.021","title":"Daily Ultrasound Imaging for Patients Undergoing Postprostatectomy Radiation Therapy Predicts and Ensures Dosimetric Endpoints","abstract":"PURPOSE: Patients who receive radiation therapy (RT) for prostate cancer are routinely positioned through radiographic means. We set out to establish a data-driven process that defines bladder volume required to meet V40/65 constraints using daily bladder ultrasound (US) and comparative cone beam CT (CBCT) before placing a patient on the treatment table. METHODS AND MATERIALS: This was a single institution retrospective study of 20 patients (390 CBCT scans) who received postprostatectomy RT. Each patient received a daily US before treatment. CBCT alignment was performed 3 times a week. The bladder and rectum were contoured on each CBCT and a session dose was recorded. A mixed-effect model was used to estimate trajectory slopes of radiation exposure with organs-at-risk volume increase. Slope differences by V40/65 for prostate fossa (PF) and pelvic lymph nodes (PF/pLN) were tested using a 3-way-interaction term with Bonferroni correction. RESULTS: . Rectal filling showed no association with CBCT volume. CONCLUSIONS: Daily US of the bladder before postprostatectomy RT allows for dosimetric predictions before daily treatment. This should translate into fewer CBCT for the patient and improved machine throughput. This technique is easy to institute and ensures organs-at-risk volumetric constraints are met based on daily US measurements.","journal":"Advances in Radiation Oncology","year":2020,"id":109270,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6007,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":522002,"name":"Rojine Ariani","orcid":"0000-0003-1929-9914","position":1,"is_corresponding":false},{"id":522003,"name":"Ethan Thio","orcid":"0000-0003-4514-4668","position":2,"is_corresponding":false},{"id":522701,"name":"Daniel Roh","orcid":null,"position":3,"is_corresponding":false},{"id":522702,"name":"Marissa Timoteo","orcid":null,"position":4,"is_corresponding":false},{"id":522004,"name":"Steven Cen","orcid":"0000-0002-7859-8909","position":5,"is_corresponding":false},{"id":522005,"name":"Xiaomeng Lei","orcid":"0000-0001-8899-5177","position":6,"is_corresponding":false},{"id":522006,"name":"Leslie K. Ballas","orcid":"0000-0001-5510-1691","position":7,"is_corresponding":false},{"id":522001,"name":"Michael Reilly","orcid":"0000-0003-2481-6728","position":0,"is_corresponding":true}],"reference_count":19,"raw_metadata":null,"created_at":"2026-07-18T23:12:50.712357Z","pmid":"33376835","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}