{"doi":"10.1016/j.actatropica.2023.106987","title":"Cytomegalovirus viremia in HIV-exposed and HIV-unexposed infants in Malawi","abstract":null,"journal":"Acta Tropica","year":2023,"id":629383,"datarank":0.24141568686511508,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":411715,"name":"Maria Franca Pirillo","orcid":"0000-0002-6186-692X","position":1,"is_corresponding":false},{"id":1629929,"name":"Stefano Orlando","orcid":null,"position":2,"is_corresponding":false},{"id":1629930,"name":"Richard Luhanga","orcid":null,"position":3,"is_corresponding":false},{"id":1629931,"name":"Robert Mphwere","orcid":null,"position":4,"is_corresponding":false},{"id":1629932,"name":"Thom Kavalo","orcid":null,"position":5,"is_corresponding":false},{"id":1086548,"name":"Mauro Andreotti","orcid":"0000-0001-5168-8624","position":6,"is_corresponding":false},{"id":1629933,"name":"Roberta Amici","orcid":null,"position":7,"is_corresponding":false},{"id":1629934,"name":"Fausto Ciccacci","orcid":null,"position":8,"is_corresponding":false},{"id":1629935,"name":"Maria Cristina Marazzi","orcid":null,"position":9,"is_corresponding":false},{"id":749543,"name":"Marco Floridia","orcid":"0000-0003-3971-0141","position":10,"is_corresponding":false},{"id":749544,"name":"Marina Giuliano","orcid":"0000-0003-2789-7797","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Cytomegalovirus viremia in HIV-exposed and HIV-unexposed infants in Malawi","abstract":"In sub-Saharan Africa the great majority of infants acquire Cytomegalovirus (CMV) infection within the first year of life. Maternal long-term antiretroviral therapy (ART) has been suggested to reduce the rate of CMV acquisition in HIV-exposed infants. In the present study serum samples collected at 6 months of age from HIV-exposed and HIV-unexposed infants were analyzed for the presence of CMV DNA (with CMV positivity defined by levels of CMV DNA > 1000 UI/ml). Twenty out of 58 (34.5%) infants had CMV DNA > 1000 UI/ml. There was no difference in the prevalence of CMV viremia between HIV-exposed and -unexposed infants [33.3% (15/45) vs 38.5% (5/13), respectively, P = 0.488]. In the HIV-exposed group, mothers of CMV-negative infants had received a longer antiretroviral treatment before delivery in comparison to mothers of CMV-positive infants (28 vs 3 months, P = 0.187). No differences in weights and lengths at birth, and at 1, 6 and 12 months were observed between CMV-positive and CMV-negative infants. In this study, the prevalence of CMV viremia at six months of age was high in infants born to HIV-positive mothers receiving long-term ART, similar to that of HIV-unexposed infants. Considering the possible relevant impact of CMV on infant health, strategies for containment of the infection should be explored.","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"37454709","pmcid":null,"openalex_id":"https://openalex.org/W4384344036","authors":[],"funders":[{"funder_name":"Agenzia Italiana per la Cooperazione allo Sviluppo","grant_id":"AID 011141/03/04","title":null},{"funder_name":"Agenzia Italiana per la Cooperazione allo Sviluppo","grant_id":"","title":null}],"total_grants":2,"fwci":0.5741,"citation_percentile":0.69630016,"influential_citations":0,"citation_trend":[{"year":2025,"count":1},{"year":2026,"count":2}],"oa_status":"closed","license":"https://doi.org/10.15223/policy-004","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0001706X23001742?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0001706X23001742?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.actatropica.2023.106987","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/37454709","host_type":"repository"},{"url":"https://hdl.handle.net/2108/388781","host_type":"repository"}],"fields_of_study":["Cytomegalovirus and herpesvirus research","HIV Research and Treatment","Parvovirus B19 Infection Studies","Infant, Newborn","Female","Humans","Infant","Pregnancy","Cytomegalovirus","Viremia","Malawi","Infectious Disease Transmission, Vertical","Cytomegalovirus Infections","HIV Infections","Pregnancy Complications, Infectious"],"mesh_terms":["Cytomegalovirus Infections","Cytomegalovirus","Female","Humans","Infant","Infant, Newborn","Malawi","Pregnancy","Pregnancy Complications, Infectious","Viremia","HIV Infections","Infectious Disease Transmission, Vertical"],"keywords":["Viremia","Cytomegalovirus","Medicine","Pediatrics","Human cytomegalovirus","Human immunodeficiency virus (HIV)","Immunology","Betaherpesvirinae","Viral disease","Herpesviridae","Virus","Malawi","Hiv-exposed Infant","Cmv Dna"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-05T18:23:21.584353Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}