{"doi":"10.1007/s13760-025-02838-4","title":"Effectiveness of telerehabilitation in reducing motor disability and enhancing quality of life in parkinson’s disease: a systematic review and meta-analysis","abstract":null,"journal":"Acta Neurologica Belgica","year":2026,"id":651272,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1698431,"name":"Mohamed Mamdouh","orcid":null,"position":1,"is_corresponding":false},{"id":1698432,"name":"Ibrahim Kamal","orcid":null,"position":2,"is_corresponding":false},{"id":1698433,"name":"Osama Khalid Abdelgawad Ahmed","orcid":null,"position":3,"is_corresponding":false},{"id":1698434,"name":"Adel Reda Abd Elwahab","orcid":null,"position":4,"is_corresponding":false},{"id":1698435,"name":"Mohammed Elkholy","orcid":null,"position":5,"is_corresponding":false},{"id":1698436,"name":"Abdelrahman G. Tawfik","orcid":null,"position":6,"is_corresponding":false},{"id":1698437,"name":"Mohamed Hesham Gamal","orcid":null,"position":7,"is_corresponding":false},{"id":1698438,"name":"Ahmed Hashem Fathallah","orcid":"0000-0002-9639-8994","position":8,"is_corresponding":false},{"id":1698430,"name":"Anas Zakarya Nourelden","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effectiveness of telerehabilitation in reducing motor disability and enhancing quality of life in parkinson’s disease: a systematic review and meta-analysis","abstract":"<h4>Objective</h4>This review and meta-analysis explored the effectiveness of telerehabilitation in reducing motor disability and improving quality of life in patients with Parkinson's disease (PD).<h4>Background</h4>PD is characterized by motor and non-motor symptoms. Motor function decline averages 3-5 points per year on the Unified Parkinson's Disease Rating Scale, Part III (UPDRS-III). Sedentary behavior worsens symptoms, while exercise improves motor function and quality of life. Telerehabilitation has proven effective in increasing exercise adherence in PD patients.<h4>Methods</h4>We searched Web of Science, Cochrane, PubMed, Scopus, and Embase for relevant articles till June 2024, including studies that compared telerehabilitation to no exercise, traditional face-to-face rehabilitation, or any studies with no comparator group. Data were pooled using a random effects model, and differences were presented using mean differences (MD) alongside 95% confidence intervals (CI).<h4>Results</h4>This review included 44 articles with 1614 participants. In assessing the quality of studies, four cohort/cross-sectional studies were rated fair, one good; one case-control study was good. Eight single-arm and four NRCTs were good, and the others were of fair quality. All 20 RCTs had a high risk of bias; one case report was deemed to have fair quality.Double-arm studies demonstrated no significant difference between telerehabilitation and in-person programs regarding UPDRS-III scores (MD: 0.69). Pooled Parkinson's Disease Questionnaire (PDQ)-39 scores exhibited the same non-significant pattern, but in longer-duration programs, telerehabilitation demonstrated a significant edge (MD:-5.45). Similarly, the difference between telerehabilitation and traditional exercise was not significant in PDQ-8 scores, nonetheless, TUG times were significantly shorter for telerehabilitation (MD: 1.17). In the single-arm analysis of telerehabilitation, UPDRS-III scores showed an improvement (MD:-2.58). Likewise, PDQ-39 scores decreased significantly (MD:-2.98). Both PDQ-8 scores (MD:-5.52) and Timed Up and Go Test (TUG) times (MD:-2.15) decreased significantly, while Activities-specific Balance Confidence (ABC) scores improved (MD: 8.65%).<h4>Conclusion</h4>Telerehabilitation decreases the progress in motor disability and improves the quality of life in PD patients, possibly due to increased exercise adherence, while costing less than in-person exercise.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"40665188","pmcid":null,"openalex_id":null,"authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://www.springernature.com/gp/researchers/text-and-data-mining","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/s13760-025-02838-4.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s13760-025-02838-4","host_type":"publisher"}],"fields_of_study":[],"mesh_terms":["Humans","Parkinson Disease","Treatment Outcome","Exercise Therapy","Quality of Life","Telerehabilitation"],"keywords":["Parkinson disease","Meta-analysis","Motor activity","Telerehabilitation"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T06:58:09.146585Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}