{"doi":"10.1007/s12630-021-02166-0","title":"Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists","abstract":null,"journal":"Canadian Journal of Anesthesia/Journal canadien d'anesthésie","year":2022,"id":674110,"datarank":0.3596842909197557,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"self_citation_contribution":0.3596842909197557,"citation_network_contribution":0.0,"self_endowment_contribution":0.3596842909197557,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1761284,"name":"Joel Neves Briard","orcid":null,"position":1,"is_corresponding":false},{"id":12538,"name":"Michael Yu","orcid":"0000-0002-9560-2017","position":2,"is_corresponding":false},{"id":1761285,"name":"Livia P. Carvalho","orcid":null,"position":3,"is_corresponding":false},{"id":1621214,"name":"Shane W. English","orcid":null,"position":4,"is_corresponding":false},{"id":1761286,"name":"Frédérick D’Aragon","orcid":null,"position":5,"is_corresponding":false},{"id":1761287,"name":"François Lauzier","orcid":null,"position":6,"is_corresponding":false},{"id":736083,"name":"Alexis F. Turgeon","orcid":"0000-0001-5675-8791","position":7,"is_corresponding":false},{"id":1761289,"name":"Sonny Dhanani","orcid":null,"position":8,"is_corresponding":false},{"id":15415,"name":"Lauralyn McIntyre","orcid":"0000-0001-7421-1407","position":9,"is_corresponding":false},{"id":1232525,"name":"Sam D. Shemie","orcid":"0000-0002-9776-1257","position":10,"is_corresponding":false},{"id":1761292,"name":"Gregory Knoll","orcid":null,"position":11,"is_corresponding":false},{"id":7314,"name":"Dean A. Fergusson","orcid":"0000-0002-3389-2485","position":12,"is_corresponding":false},{"id":1147550,"name":"Samantha J. Anthony","orcid":"0000-0002-1800-2333","position":13,"is_corresponding":false},{"id":300974,"name":"Matthew J. Weiss","orcid":"0000-0003-0553-248X","position":14,"is_corresponding":false},{"id":619014,"name":"Michaël Chassé","orcid":"0000-0001-7075-1924","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists","abstract":"<h4>Purpose</h4>Trust in the deceased organ donation process relies on the expectation that the diagnosis of death by neurologic criteria (DNC) is accurate and reliable. The objective of this study was to assess the perceptions and approaches to DNC diagnosis among Canadian intensivists.<h4>Methods</h4>We conducted a self-administered, online, cross-sectional survey of Canadian intensivists. Our sampling frame included all intensivists practicing in Canadian institutions. Results are reported using descriptive statistics.<h4>Results</h4>Among 550 identified intensivists, 249 (45%) completed the survey. Respondents indicated they would be comfortable diagnosing DNC based on clinical criteria alone in cases where there is movement in response to stimulation (119/248; 48%); inability to evaluate upper/lower extremity responses (84/249; 34%); spontaneous peripheral movement (76/249; 31%); inability to evaluate both oculocephalic and oculo-caloric reflexes (40/249; 16%); presence of high cervical spinal cord injury (40/249; 16%); and within 24 hr of hypoxemic-ischemic brain injury (38/247; 15%). Most respondents agreed that an ancillary test should always be conducted when a complete clinical evaluation is impossible (225/241; 93%); when there is possibility of a residual sedative effect (216/242; 89%); when the mechanism for brain injury is unclear (172/241; 71%); and if isolated brainstem injury is suspected (142/242; 59%). Sixty-six percent (158/241) believed that ancillary tests are sensitive and 55% (132/241) that they are specific for DNC. Respondents considered the following ancillary tests useful for DNC: four-vessel conventional angiography (211/241; 88%), nuclear imaging (179/240; 75%), computed tomography (CT) angiography (156/240; 65%), and CT perfusion (134/240; 56%).<h4>Conclusion</h4>There is variability in perceptions and approaches to DNC diagnosis among Canadian intensivists, and some practices are inconsistent with national recommendations.","is_dataset_classified":null,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34931292","pmcid":null,"openalex_id":"https://openalex.org/W4200507069","authors":[],"funders":[{"funder_name":"Canadian Institutes of Health Research","grant_id":"unidentified","title":"unidentified"},{"funder_name":"Canada Excellence Research Chairs, Government of Canada","grant_id":"","title":null},{"funder_name":"Fondation du CHUM","grant_id":"","title":null},{"funder_name":"Fonds de Recherche du Québec - Santé","grant_id":"","title":null}],"total_grants":4,"fwci":1.7093,"citation_percentile":0.8471667,"influential_citations":0,"citation_trend":[{"year":2022,"count":2},{"year":2023,"count":7},{"year":2025,"count":1}],"oa_status":"bronze","license":"Springer Nature TDM","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/s12630-021-02166-0.pdf","host_type":"journal"},{"url":"https://link.springer.com/content/pdf/10.1007/s12630-021-02166-0.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s12630-021-02166-0/fulltext.html","host_type":"publisher"},{"url":"https://doi.org/10.1007/s12630-021-02166-0","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34931292","host_type":"repository"}],"fields_of_study":["Organ Donation and Transplantation","Autopsy Techniques and Outcomes","Organ Transplantation Techniques and Outcomes","03 medical and health sciences","0302 clinical medicine"],"mesh_terms":["Brain Death","Canada","Cross-Sectional Studies","Humans","Tissue and Organ Procurement"],"keywords":["Cross-sectional study","Medicine","Survey research","Emergency medicine","Family medicine","Pathology","Psychology","Survey","Clinical evaluation","Clinical examination","Brain Death","Ancillary Test","Death By Neurologic Criteria","Neurologic Determination Of Death","Canada","Cross-Sectional Studies","Tissue and Organ Procurement","Humans"],"sdg_mappings":[{"sdg_number":2,"sdg_label":"2. Zero hunger"},{"sdg_number":3,"sdg_label":"3. Good health"},{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-16T15:39:07.337332Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}