{"doi":"10.1007/s12325-026-03693-2","title":"Racial and Ethnic Patterns Observed in Inflammatory Bowel Disease Prevalence, Clinical Burden, and Healthcare Resource Utilization in the United States: Findings from an Administrative Claims Database","abstract":null,"journal":"Advances in Therapy","year":2026,"id":645755,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1681622,"name":"Shannon Ferrante","orcid":null,"position":1,"is_corresponding":false},{"id":1681623,"name":"Myrlene Sanon","orcid":null,"position":2,"is_corresponding":false},{"id":1681624,"name":"Sumesh Kachroo","orcid":"0000-0002-7190-6323","position":3,"is_corresponding":false},{"id":1681621,"name":"Aarti A. Patel","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Racial and Ethnic Patterns Observed in Inflammatory Bowel Disease Prevalence, Clinical Burden, and Healthcare Resource Utilization in the United States: Findings from an Administrative Claims Database","abstract":"<h4>Introduction</h4>Inflammatory bowel disease (IBD) is a chronic, immune-mediated gastrointestinal disorder comprised of Crohn's disease (CD) and ulcerative colitis (UC). Real-world data on racial differences in disease burden, treatment patterns, and healthcare resource utilization (HCRU) remain limited.<h4>Methods</h4>The retrospective observational study was conducted using Optum's de-identified Clinformatics<sup>®</sup> Data Mart Database (Optum<sup>®</sup> CDM) in the US. Data from adult patients with a diagnosis of CD and/or UC between January 1, 2010, and September 30, 2022, were extracted and analyzed to assess the prevalence of IBD, complicated/penetrating CD, and extraintestinal manifestations (EIMs) across different races/ethnicities in the US. The treatment use, HCRU, and symptomatic and psychosocial burden among patients pre-and post-IBD diagnosis were also assessed among patients stratified by race/ethnicity.<h4>Results</h4>A total of 271,059 patients included in the analysis were predominantly White (76.6%) followed by Black (7.9%), Hispanic (6.1%), and Asian (2.6%). IBD prevalence rose from 0.5% (2010) to 2.2% (2022). In 2022, prevalence was highest among White (2.5%) followed by Black (1.9%), Asian (1.4%), and Hispanic individuals (1.3%). Among patients with CD and UC, respectively, EIM prevalence rose from 38.4% and 31.5% in 2016 to 57.5% and 43.2% in 2022. Corticosteroids and biologics were prescribed to 38.8% and 52.8% of patients with CD and UC post-diagnosis, respectively. IBD-related HCRU increased after diagnosis, particularly among acute care patients, and was highest in Black individuals.<h4>Conclusion</h4>The results highlight an increased prevalence of IBD among patients from different racial and ethnic backgrounds. The study further provides insights into the IBD-related outcomes, treatment use, and HCRU patterns among diverse racial and ethnic groups and underlines the present unmet need for further research.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"42423953","pmcid":null,"openalex_id":"https://openalex.org/W7167825457","authors":[],"funders":[{"funder_name":"Johnson and Johnson Innovation","grant_id":"","title":null}],"total_grants":1,"fwci":0.0,"citation_percentile":0.8545204,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://www.springernature.com/gp/researchers/text-and-data-mining","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/s12325-026-03693-2.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s12325-026-03693-2","host_type":"publisher"},{"url":"https://doi.org/10.1007/s12325-026-03693-2","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/42423953","host_type":"repository"}],"fields_of_study":["Inflammatory Bowel Disease","Pregnancy and Medication Impact","Autoimmune and Inflammatory Disorders"],"mesh_terms":[],"keywords":["Inflammatory bowel disease","Ethnic group","Ulcerative colitis","Psychosocial","Disease","Health care","Epidemiology","Comorbidity","Logistic regression","Retrospective Study","Race/ethnicity","Crohn’s Disease","Outcome Research"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-09T10:02:20.213240Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}