{"doi":"10.1007/s10562-020-03271-3","title":"Synthesis of N-Substituted Indoles via Aqueous Ring-Closing Metathesis","abstract":null,"journal":"Catalysis Letters","year":2021,"id":677543,"datarank":0.3596842909197557,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"self_citation_contribution":0.3596842909197557,"citation_network_contribution":0.0,"self_endowment_contribution":0.3596842909197557,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1770339,"name":"Dario Staub","orcid":null,"position":1,"is_corresponding":false},{"id":225331,"name":"Thomas R. Ward","orcid":"0000-0001-8602-5468","position":2,"is_corresponding":false},{"id":1770335,"name":"Valerio Sabatino","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Synthesis of N-Substituted Indoles via Aqueous Ring-Closing Metathesis","abstract":"We report herein the synthesis of N-substituted indoles resulting from the ring-closing metathesis of indole precursors bearing N-terminal alkenes. The aqueous metathesis of the indole precursors gave good yields of N-substituted indoles (up to 72%) with commercial metathesis catalysts and with artificial metalloenzymes based on the biotin-streptavidin technology. Strikingly, the yield of the N-acetylindole increases in presence of a second metathesis substrate.","is_dataset_classified":null,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26207759","pmcid":null,"openalex_id":"https://openalex.org/W3034134211","authors":[],"funders":[{"funder_name":"H2020 European Research Council","grant_id":"DrEAM advanced grant 694424","title":null},{"funder_name":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","grant_id":"grant 200020_182046","title":null},{"funder_name":"European Commission","grant_id":"694424","title":"Directed Evolution of Artificial Metalloenzymes for In Vivo Applications"},{"funder_name":"Swiss National Science Foundation","grant_id":"182046","title":"Directed Evolution of Artificial Metalloproteins and Metalloenzymes"}],"total_grants":4,"fwci":0.4768,"citation_percentile":0.54787547,"influential_citations":0,"citation_trend":[{"year":2020,"count":1},{"year":2021,"count":2},{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":3},{"year":2025,"count":2}],"oa_status":"green","license":"other-oa","oa_locations":[{"url":"https://edoc.unibas.ch/77560/1/Indole%20RCM_revised%20manuscript.pdf","host_type":"repository"},{"url":"https://edoc.unibas.ch/77560/1/Indole%20RCM_revised%20manuscript.pdf","host_type":"repository"},{"url":"https://link.springer.com/content/pdf/10.1007/s10562-020-03271-3.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s10562-020-03271-3/fulltext.html","host_type":"publisher"},{"url":"https://doi.org/10.1007/s10562-020-03271-3","host_type":"journal"},{"url":"https://dx.doi.org/10.5451/unibas-ep77560","host_type":""},{"url":"https://dx.doi.org/10.1007/s10562-020-03271-3","host_type":""},{"url":"http://dx.doi.org/10.1007/s10562-020-03271-3","host_type":""},{"url":"https://doi.org/https://doi.org/10.1007/s10562-020-03271-3","host_type":""}],"fields_of_study":["Synthetic Organic Chemistry Methods","Chemical Synthesis and Analysis","Synthesis and Catalytic Reactions","01 natural sciences","0104 chemical sciences"],"mesh_terms":[],"keywords":["Metathesis","Ring-closing metathesis","Chemistry","Catalysis","Salt metathesis reaction","Ring-opening metathesis polymerisation","Indole test","Combinatorial chemistry","Yield (engineering)","Aqueous solution","Organic chemistry"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T04:15:50.026577Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}